PRPS1 Gene Record

  • PRPS1 5631 Druggable GenomeDrug Resistance

    Alternate Names:

    5631
    PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE 1
    PRPS1
    ARTS
    CMTX5
    DFN2
    DFNX1
    PPRibP
    PRS-I
    PRSI
    311850
    9462
    ENSG00000147224
    OTTHUMG00000022167
    PRPS1_HUMAN
    P60891
    RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 1
    RIBOSE-PHOSPHATE PYROPHOSPHOKINASE I (EC 2.7.6.1) (PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE I) (PRS-I) (PPRIBP). [SOURCE:UNIPROT/SWISSPROT;ACC:P60891]
    4566

    Gene Info:

    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Interpro Name Phosphoribosyltransferase
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR000836
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name PRibTrfase
    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    KINASE
    DRUG RESISTANCE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • Ensembl: ENSG00000147224

    • Version: 101_38

    Alternate Names:
    PRPS1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000147224

    • Version: 26-July-2011

    Alternate Names:
    PRPS1 Display Id
    ENSG00000147224 Ensembl Gene Id
    RIBOSE-PHOSPHATE PYROPHOSPHOKINASE I (EC 2.7.6.1) (PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE I) (PRS-I) (PPRIBP). [SOURCE:UNIPROT/SWISSPROT;ACC:P60891] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: P60891

    • Version: 11-September-2012

    Alternate Names:
    P60891 Uniprot Accession
    PRPS1_HUMAN Uniprot Id
    PRPS1 Uniprot Gene Name

    Gene Info:
    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Interpro Name Phosphoribosyltransferase

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • CIViC: PRPS1

    • Version: 14-September-2020

    Alternate Names:
    5631 Entrez Gene ID
    4566 CIViC Gene ID

    Gene Info:

    Gene Categories:
    DRUG RESISTANCE

    Publications:
    Li B et al., 2015, Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL., Nat Med

  • HumanProteinAtlas: PRPS1

    • Version: 19.3

    Alternate Names:
    ENSG00000147224 Ensembl Gene ID
    CMTX5 Human Protein Atlas Gene Synonym
    DFN2 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • Pharos: PRPS1

    • Version: 01-February-2022

    Alternate Names:
    Ribose-phosphate pyrophosphokinase 1 Gene Name
    P60891 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ENZYME

    Publications:

  • GO: PRPS1

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    KINASE

    Publications: