PRSS1 Gene Record

  • PRSS1 5644 Druggable Genome

    Alternate Names:

    5644
    PROTEASE, SERINE 1
    PRSS1
    TRP1
    TRY1
    TRY4
    TRYP1
    276000
    9475
    ENSG00000204983
    OTTHUMG00000158923
    P07477
    ALPHA-TRYPSIN CHAIN 2
    TRY1_HUMAN
    ENSG00000261473
    ENSG00000173636
    TRYPSIN I PRECURSOR (EC 3.4.21.4) (CATIONIC TRYPSINOGEN). [SOURCE:UNIPROT/SWISSPROT;ACC:P07477]
    serine protease 1
    Cationic trypsinogen
    T27602
    Trypsin-1

    Gene Info:

    Uniprot Status Swiss-Prot
    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name Peptidase_S1_S6
    Human Readable Name PROTEASE
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Interpro Name Peptidase S1/S6, chymotrypsin/Hap
    Interpro Acc IPR001254
    Target Class Enzymes
    Target Subclass EC:3.4.21.4
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    PROTEASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • ULINASTATIN   PRSS1

    Interaction Score: 12.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • CYANOPEPTOLIN SS   PRSS1

    Interaction Score: 4.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CYANOPEPTOLIN S   PRSS1

    Interaction Score: 4.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MELAGATRAN   PRSS1

    Interaction Score: 2.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • BORTEZOMIB   PRSS1

    Interaction Score: 0.41

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20875739


    Sources:
    DTC TTD

  • Ensembl: ENSG00000204983

    • Version: 101_38

    Alternate Names:
    PRSS1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P07477

    • Version: January-2014

    Alternate Names:
    PRSS1 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.4.21.4

    Publications:

  • RussLampel: ENSG00000173636

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000173636 Ensembl Gene Id
    PRSS1 Display Id
    TRYPSIN I PRECURSOR (EC 3.4.21.4) (CATIONIC TRYPSINOGEN). [SOURCE:UNIPROT/SWISSPROT;ACC:P07477] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: P07477

    • Version: 11-September-2012

    Alternate Names:
    PRSS1 Uniprot Gene Name
    ENSG00000204983 Ensembl Gene Id
    P07477 Uniprot Accession

    Gene Info:
    Uniprot Status Swiss-Prot
    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name Peptidase_S1_S6

    Gene Categories:
    PROTEASE, DRUGGABLE GENOME

    Publications:

  • DTC: PRSS1

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Blackburn C et al., 2010, Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome., Bioorg Med Chem Lett

  • HingoraniCasas: ENSG00000204983

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000204983 Gene Symbol
    PRSS1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Tempus: PRSS1

    • Version: 11-November-2018

    Alternate Names:
    PRSS1 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • dGene: PRSS1

    • Version: 27-Jun-2013

    Alternate Names:
    5644 Gene ID
    TRP1 dGene Synonym
    TRY1 dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

  • TTD: Cationic trypsinogen

    • Version: 2020.06.01

    Alternate Names:
    PRSS1 TTD Gene Abbreviation
    T27602 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: PRSS1

    • Version: 01-February-2022

    Alternate Names:
    Trypsin-1 Gene Name
    P07477 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications: