RPS6KA6 Gene Record

  • RPS6KA6 27330 Druggable Genome

    Alternate Names:

    27330
    RIBOSOMAL PROTEIN S6 KINASE A6
    RPS6KA6
    PP90RSK4
    RSK-4
    RSK4
    S6K-alpha-6
    p90RSK6
    300303
    10435
    ENSG00000072133
    OTTHUMG00000021923
    Q9UK32
    KS6A6_HUMAN
    RIBOSOMAL PROTEIN S6 KINASE ALPHA-6
    RIBOSOMAL PROTEIN S6 KINASE ALPHA 6 (EC 2.7.1.37) (S6K-ALPHA 6) (90 KDA RIBOSOMAL PROTEIN S6 KINASE 6) (P90-RSK 6) (RIBOSOMAL S6 KINASE 4) (RSK-4) (PP90RSK4). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9UK32]
    RSK6
    T95878

    Gene Info:

    Interpro Acc IPR002290
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Status Swiss-Prot
    Human Readable Name KINASE
    Interpro Type Domain
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME

    Publications:

  • CHEMBL573107   RPS6KA6

    Interaction Score: 7.73

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • CEP-1347   RPS6KA6

    Interaction Score: 6.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24044867


    Sources:
    DTC

  • Ensembl: ENSG00000072133

    • Version: 101_38

    Alternate Names:
    RPS6KA6 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: Q9UK32

    • Version: 11-September-2012

    Alternate Names:
    RIBOSOMAL PROTEIN S6 KINASE ALPHA-6 Uniprot Protein Name
    RPS6KA6 Uniprot Gene Name
    ENSG00000072133 Ensembl Gene Id

    Gene Info:
    Interpro Acc IPR002290
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000072133

    • Version: 26-July-2011

    Alternate Names:
    RPS6KA6 Display Id
    ENSG00000072133 Ensembl Gene Id
    RIBOSOMAL PROTEIN S6 KINASE ALPHA 6 (EC 2.7.1.37) (S6K-ALPHA 6) (90 KDA RIBOSOMAL PROTEIN S6 KINASE 6) (P90-RSK 6) (RIBOSOMAL S6 KINASE 4) (RSK-4) (PP90RSK4). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9UK32] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • DTC: RPS6KA6

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Goodfellow VS et al., 2013, Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3., J Med Chem

  • HingoraniCasas: ENSG00000072133

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000072133 Gene Symbol
    RPS6KA6 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: RPS6KA6

    • Version: 01-February-2022

    Alternate Names:
    RSK4 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • dGene: RPS6KA6

    • Version: 27-Jun-2013

    Alternate Names:
    27330 Gene ID
    PP90RSK4 dGene Synonym
    RSK4 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: Ribosomal protein S6 kinase alpha-6

    • Version: 2020.06.01

    Alternate Names:
    RSK6 TTD Gene Abbreviation
    T95878 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: RPS6KA6

    • Version: 01-February-2022

    Alternate Names:
    Ribosomal protein S6 kinase alpha-6 Gene Name
    Q9UK32 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: