S1PR4 Gene Record

  • S1PR4 8698 Druggable Genome

    Alternate Names:

    8698
    SPHINGOSINE-1-PHOSPHATE RECEPTOR 4
    S1PR4
    EDG6
    LPC1
    S1P4
    SLP4
    603751
    3170
    ENSG00000125910
    OTTHUMG00000180672
    Sphingosine 1-phosphate receptor Edg-6
    S1P receptor Edg-6
    S1P receptor 4
    Endothelial differentiation G-protein coupled receptor 6
    Sphingosine 1-phosphate receptor 4
    SPHINGOSINE 1-PHOSPHATE RECEPTOR EDG-6 (S1P RECEPTOR EDG-6) (ENDOTHELIAL DIFFERENTIATION G-PROTEIN COUPLED RECEPTOR 6) (SPHINGOSINE 1-PHOSPHATE RECEPTOR 4) (S1P4). [SOURCE:UNIPROT/SWISSPROT;ACC:O95977]
    O95977
    S1PR4_HUMAN

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Interpro Name GPCR, rhodopsin-like, 7TM
    Interpro Type Family
    Interpro Acc IPR000276
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    G PROTEIN COUPLED RECEPTOR
    DRUGGABLE GENOME

    Publications:

  • AMISELIMOD HYDROCHLORIDE   S1PR4

    Interaction Score: 1.55

    Interaction Types & Directionality:
    modulator

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Sphingosine 1-phosphate receptor modulator

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • FINGOLIMOD HYDROCHLORIDE   S1PR4

    Interaction Score: 1.55

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Sphingosine 1-phosphate receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CHEMBL586135   S1PR4

    Interaction Score: 0.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL579318   S1PR4

    Interaction Score: 0.77

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL171699   S1PR4

    Interaction Score: 0.77

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1362503   S1PR4

    Interaction Score: 0.7

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ISOVELLERAL   S1PR4

    Interaction Score: 0.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • 9,10-PHENANTHRENEQUINONE   S1PR4

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000125910

    • Version: 101_38

    Alternate Names:
    S1PR4 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: O95977

    • Version: 11-September-2012

    Alternate Names:
    O95977 Uniprot Accession
    S1PR4 Uniprot Gene Name
    ENSG00000125910 Ensembl Gene Id

    Gene Info:
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Interpro Name GPCR, rhodopsin-like, 7TM
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000125910

    • Version: 26-July-2011

    Alternate Names:
    SPHINGOSINE 1-PHOSPHATE RECEPTOR EDG-6 (S1P RECEPTOR EDG-6) (ENDOTHELIAL DIFFERENTIATION G-PROTEIN COUPLED RECEPTOR 6) (SPHINGOSINE 1-PHOSPHATE RECEPTOR 4) (S1P4). [SOURCE:UNIPROT/SWISSPROT;ACC:O95977] Description
    ENSG00000125910 Ensembl Gene Id
    EDG6 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000125910

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000125910 Gene Symbol
    S1PR4 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: EDG6

    • Version: chembl_23

    Alternate Names:
    EDG6 GENE_SYMBOL
    S1PR4 GENE_SYMBOL
    Sphingosine 1-phosphate receptor 4 UNIPROT

    Gene Info:

    Publications:

  • GO: S1PR4

    • Version: 01-February-2022

    Alternate Names:
    EDG6 GO Gene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

  • dGene: S1PR4

    • Version: 27-Jun-2013

    Alternate Names:
    8698 Gene ID
    EDG6 dGene Synonym
    LPC1 dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

  • DTC: S1PR4

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: