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SCNN1G 6340 Druggable Genome
Alternate Names:
6340 SODIUM CHANNEL EPITHELIAL 1 GAMMA SUBUNIT SCNN1G BESC3 ENaCg ENaCgamma PHA1 SCNEG 600761 10602 ENSG00000166828 OTTHUMG00000131609 PA307 SCNNG_HUMAN P51170 AMILORIDE-SENSITIVE SODIUM CHANNEL GAMMA-SUBUNIT (EPITHELIAL NA+ CHANNEL GAMMA SUBUNIT) (GAMMA ENAC) (NONVOLTAGE-GATED SODIUM CHANNEL 1 GAMMA SUBUNIT) (SCNEG) (GAMMA NACH). [SOURCE:UNIPROT/SWISSPROT;ACC:P51170] Epithelial Na(+) channel subunit gamma Gamma-NaCH Nonvoltage-gated sodium channel 1 subunit gamma Gamma-ENaC Amiloride-sensitive sodium channel subunit gamma SODIUM CHANNEL EPITHELIAL 1 SUBUNIT GAMMA LDLS2 Gene Info:
Human Readable Name DRUGGABLE GENOME Target Class Transporters Target Subclass TC:1.A.6.1.1 Uniprot Status Swiss-Prot Interpro Acc IPR001873 Interpro Type Family Interpro Name Na+ channel, amiloride-sensitive Human Readable Name ION CHANNEL Interpro Short Name Na+channel_ASC Uniprot Evidence 1: Evidence at protein level Target Main Class Transporters Transmembrane Helix Count 2 Target Subclass Amiloride-sensitive Na+ channel Target Subclass Channels Gene Biotype PROTEIN_CODING Gene Categories: Category Details
ION CHANNEL EXTERNAL SIDE OF PLASMA MEMBRANE DRUGGABLE GENOME Publications:
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Interaction Score: 8.59
Interaction Types & Directionality:
blocker (inhibitory) inhibitor (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target Mechanism of Interaction Amiloride-sensitive sodium channel, ENaC blocker
Sources:
TdgClinicalTrial ChemblInteractions TEND PharmGKB -
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Mechanism of Interaction Amiloride-sensitive sodium channel, ENaC blocker Direct Interaction yes -
Interaction Score: 3.86
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Mechanism of Interaction Amiloride-sensitive sodium channel, ENaC blocker Direct Interaction yes
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- Version: 101_38
Alternate Names:
SCNN1G Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: January-2014
Alternate Names:
SCNN1G Gene Symbol Gene Info:
Target Class Transporters Target Subclass TC:1.A.6.1.1 Publications:
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- Version: 11-September-2012
Alternate Names:
SCNNG_HUMAN Uniprot Id AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT GAMMA Uniprot Protein Name SCNN1G Uniprot Gene Name Gene Info:
Uniprot Status Swiss-Prot Interpro Acc IPR001873 Interpro Type Family Gene Categories:
ION CHANNEL, DRUGGABLE GENOME Publications:
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Alternate Names:
ENSG00000166828 Ensembl Gene Id SCNNG_HUMAN Uniprot Id SCNN1G Gene Symbol Gene Info:
Target Main Class Transporters Transmembrane Helix Count 2 Target Subclass Amiloride-sensitive Na+ channel Publications:
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- Version: 26-July-2011
Alternate Names:
SCNN1G Display Id ENSG00000166828 Ensembl Gene Id AMILORIDE-SENSITIVE SODIUM CHANNEL GAMMA-SUBUNIT (EPITHELIAL NA+ CHANNEL GAMMA SUBUNIT) (GAMMA ENAC) (NONVOLTAGE-GATED SODIUM CHANNEL 1 GAMMA SUBUNIT) (SCNEG) (GAMMA NACH). [SOURCE:UNIPROT/SWISSPROT;ACC:P51170] Description Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
PA307 PharmGKB ID Gene Info:
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- Version: chembl_23
Alternate Names:
SCNN1G GENE_SYMBOL Amiloride-sensitive sodium channel subunit gamma UNIPROT Epithelial Na(+) channel subunit gamma UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000166828 Gene Symbol SCNN1G Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
Amiloride-sensitive sodium channel subunit gamma Gene Name P51170 UniProt ID Gene Info:
Gene Categories:
ION CHANNEL Publications:
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Alternate Names:
Gene Info:
Gene Categories:
ION CHANNEL, EXTERNAL SIDE OF PLASMA MEMBRANE Publications: