462 |
SERPIN FAMILY C MEMBER 1 |
SERPINC1 |
AT3 |
AT3D |
ATIII |
THPH7 |
107300 |
775 |
ENSG00000117601 |
OTTHUMG00000037276 |
P01008 |
ANT3_HUMAN |
ANTITHROMBIN-III |
Serpin C1 |
ANTITHROMBIN-III PRECURSOR (ATIII). [SOURCE:UNIPROT/SWISSPROT;ACC:P01008] |
PA35026 |
T73476 |
ATIII-R2 |
ATIII-T1 |
ATIII-T2 |
Target Main Class | Other |
Target Subclass | Enzyme Inhibitor |
Human Readable Name | PROTEASE INHIBITOR |
Human Readable Name | DRUGGABLE GENOME |
Interpro Short Name | Serpin_fam |
Interpro Acc | IPR000215 |
Interpro Type | Family |
Interpro Name | Serpin family |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Target Class | Miscellaneous |
Target Subclass | Enzyme regulator |
Target Class | Other |
Gene Biotype | PROTEIN_CODING |
PROTEASE INHIBITOR |
DRUGGABLE GENOME |
activator (activating) |
potentiator |
Mechanism of Interaction | Antithrombin-III activator |
Direct Interaction | yes |
activator (activating) |
potentiator |
Trial Name | tinzaparin sodium injection,Innohep |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Antithrombin-III inhibitor |
Direct Interaction | yes |
activator (activating) |
Mechanism of Interaction | Antithrombin-III activator |
Direct Interaction | yes |
activator (activating) |
Mechanism of Interaction | Antithrombin-III activator |
Direct Interaction | yes |
activator (activating) |
Mechanism of Interaction | Antithrombin-III activator |
Direct Interaction | yes |
activator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Antithrombin-III activator |
activator (activating) |
Mechanism of Interaction | Antithrombin-III activator |
Direct Interaction | yes |
activator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Antithrombin-III activator |
activator (activating) |
Mechanism of Interaction | Antithrombin-III activator |
Direct Interaction | yes |
n/a |
Combination therapy | Estradiol,Progesterone |
n/a |
Combination therapy | Estradiol,Progesterone |
SERPINC1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
462 | Entrez Gene Id |
SERPINC1 | Gene Symbol |
ANT3_HUMAN | Uniprot Id |
Target Main Class | Other |
Target Subclass | Enzyme Inhibitor |
ENSG00000117601 | Ensembl Gene Id |
ANTITHROMBIN-III PRECURSOR (ATIII). [SOURCE:UNIPROT/SWISSPROT;ACC:P01008] | Description |
SERPINC1 | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
SERPINC1 | Gene Symbol |
Target Class | Miscellaneous |
Target Subclass | Enzyme regulator |
Target Class | Other |
SERPINC1 | Uniprot Gene Name |
P01008 | Uniprot Accession |
462 | Entrez Gene Id |
Human Readable Name | DRUGGABLE GENOME |
Interpro Short Name | Serpin_fam |
Interpro Acc | IPR000215 |
PROTEASE INHIBITOR, DRUGGABLE GENOME |
PA35026 | PharmGKB ID |
ATIII | TTD Gene Abbreviation |
T73476 | TTD Target ID |
ENSG00000117601 | Gene Symbol |
SERPINC1 | Ensembl Id |
DRUGGABLE GENOME |
AT3 | GENE_SYMBOL |
SERPINC1 | GENE_SYMBOL |
Antithrombin-III | UNIPROT |
462 | Gene ID |
AT3 | dGene Synonym |
AT3D | dGene Synonym |
PROTEASE INHIBITOR |