SRMS Gene Record

  • SRMS 6725 Druggable Genome

    Alternate Names:

    6725
    SRC-RELATED KINASE LACKING C-TERMINAL REGULATORY TYROSINE AND N-TERMINAL MYRISTYLATION SITES
    SRMS
    C20orf148
    PTK70
    SRM
    dJ697K14.1
    11298
    ENSG00000125508
    OTTHUMG00000032977
    Q9H3Y6
    SRMS_HUMAN
    TYROSINE-PROTEIN KINASE SRMS (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9H3Y6]
    TYROSINE-PROTEIN KINASE SRMS
    617797

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Human Readable Name KINASE
    Interpro Type Domain
    Uniprot Evidence 2: Evidence at transcript level
    Interpro Acc IPR001245
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME

    Publications:

  • TG100-801   SRMS

    Interaction Score: 0.48

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction SRC inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • XL-228   SRMS

    Interaction Score: 0.48

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction SRC inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • ENMD-981693   SRMS

    Interaction Score: 0.29

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DASATINIB   SRMS

    Interaction Score: 0.22

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    DTC ChemblInteractions

  • OSI-632   SRMS

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ILORASERTIB   SRMS

    Interaction Score: 0.15

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    DTC ChemblInteractions

  • LINIFANIB   SRMS

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   SRMS

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000125508

    • Version: 101_38

    Alternate Names:
    SRMS Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: Q9H3Y6

    • Version: 11-September-2012

    Alternate Names:
    6725 Entrez Gene Id
    ENSG00000125508 Ensembl Gene Id
    Q9H3Y6 Uniprot Accession

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Human Readable Name KINASE

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000125508

    • Version: 26-July-2011

    Alternate Names:
    SRMS Display Id
    ENSG00000125508 Ensembl Gene Id
    TYROSINE-PROTEIN KINASE SRMS (EC 2.7.1.112). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9H3Y6] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: C20orf148

    • Version: chembl_23

    Alternate Names:
    C20orf148 GENE_SYMBOL
    SRMS GENE_SYMBOL
    Tyrosine-protein kinase Srms UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000125508

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000125508 Gene Symbol
    SRMS Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: SRMS

    • Version: 01-February-2022

    Alternate Names:
    C20orf148 GO Gene Synonym

    Gene Info:

    Gene Categories:
    TYROSINE KINASE

    Publications:

  • dGene: SRMS

    • Version: 27-Jun-2013

    Alternate Names:
    6725 Gene ID
    C20orf148 dGene Synonym
    SRM dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, TYROSINE KINASE

    Publications:

  • Pharos: SRMS

    • Version: 01-February-2022

    Alternate Names:
    Tyrosine-protein kinase Srms Gene Name
    Q9H3Y6 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • DTC: SRMS

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: