6850 |
SPLEEN ASSOCIATED TYROSINE KINASE |
SYK |
p72-Syk |
600085 |
11491 |
ENSG00000165025 |
OTTHUMG00000020200 |
TYROSINE-PROTEIN KINASE SYK (EC 2.7.1.112) (SPLEEN TYROSINE KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P43405] |
P43405 |
spleen tyrosine kinase |
Tyrosine-protein kinase SYK |
5572 |
KSYK_HUMAN |
T62431 |
IMD82 |
Human Readable Name | DRUGGABLE GENOME |
Target Class | Enzymes |
Target Subclass | EC:2.7.10.2 |
Interpro Short Name | Ser-Thr/Tyr_kinase_cat_dom |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Acc | IPR001245 |
Uniprot Status | Swiss-Prot |
Human Readable Name | KINASE |
Interpro Type | Domain |
Interpro Name | Serine-threonine/tyrosine-protein kinase catalytic domain |
Initial Gene Query | SYK |
Counted Citations from 1950-2000 | 1882 |
Gene Biotype | PROTEIN_CODING |
KINASE |
SERINE THREONINE KINASE |
TYROSINE KINASE |
DRUG RESISTANCE |
DRUGGABLE GENOME |
CLINICALLY ACTIONABLE |
inhibitor (inhibitory) |
Trial Name | Fostamatinib |
Novel drug target | Novel Target |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase SYK inhibitor |
Direct Interaction | yes |
SYK | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
SYK | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:2.7.10.2 |
P43405 | Uniprot Accession |
SYK | Uniprot Gene Name |
TYROSINE-PROTEIN KINASE SYK | Uniprot Protein Name |
Interpro Short Name | Ser-Thr/Tyr_kinase_cat_dom |
Uniprot Evidence | 1: Evidence at protein level |
Human Readable Name | DRUGGABLE GENOME |
KINASE, DRUGGABLE GENOME |
6850 | Entrez Gene ID |
Initial Gene Query | SYK |
Counted Citations from 1950-2000 | 1882 |
KINASE |
SYK | Display Id |
ENSG00000165025 | Ensembl Gene Id |
TYROSINE-PROTEIN KINASE SYK (EC 2.7.1.112) (SPLEEN TYROSINE KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P43405] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
6850 | Entrez Gene ID |
5572 | CIViC Gene ID |
DRUG RESISTANCE |
SYK | TTD Gene Abbreviation |
T62431 | TTD Target ID |
ENSG00000165025 | Gene Symbol |
SYK | Ensembl Id |
DRUGGABLE GENOME |
6850 | Entrez Gene Id |
SYK | MyCancerGenome Gene Symbol |
SYK | MyCancerGenome Reported Gene Name |
SYK | GENE_SYMBOL |
Tyrosine-protein kinase SYK | UNIPROT |
Spleen tyrosine kinase | UNIPROT |
SYK | Gene Symbol |
CLINICALLY ACTIONABLE |
6850 | Gene ID |
p72-Syk | dGene Synonym |
KINASE, TYROSINE KINASE |
Tyrosine-protein kinase SYK | Gene Name |
P43405 | UniProt ID |
KINASE |
CLINICALLY ACTIONABLE |
SERINE THREONINE KINASE, TYROSINE KINASE |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |