TNFRSF8 Gene Record

  • TNFRSF8 943 Druggable Genome

    Alternate Names:

    943
    TNF RECEPTOR SUPERFAMILY MEMBER 8
    TNFRSF8
    CD30
    D1S166E
    Ki-1
    153243
    11923
    ENSG00000120949
    OTTHUMG00000001827
    PA36616
    P28908
    CD_antigen=CD30
    Lymphocyte activation antigen CD30
    Ki-1 antigen
    CD30L receptor
    Tumor necrosis factor receptor superfamily member 8
    T88023

    Gene Info:

    Target Class Receptors
    Target Subclass Receptors
    Target Subclass TNFNGF
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

  • IRATUMUMAB   TNFRSF8

    Interaction Score: 30.91

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Tumor necrosis factor receptor superfamily member 8 other
    Direct Interaction yes
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions TTD

  • SGN-30   TNFRSF8

    Interaction Score: 20.61

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Tumor necrosis factor receptor superfamily member 8 agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • XMAB-2513   TNFRSF8

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • BRENTUXIMAB   TNFRSF8

    Interaction Score: 10.3

    Interaction Types & Directionality:
    antibody (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • TAFASITAMAB   TNFRSF8

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name MOR208
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • BRENTUXIMAB VEDOTIN   TNFRSF8

    Interaction Score: 0.69

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tumor necrosis factor receptor superfamily member 8 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions