DGIdb - ALMITRINE Drug Record

ALMITRINE chembl:CHEMBL1183717 Approved

Alternate Names:

ALMITRINE
2,4-BIS(ALLYLAMINO)-6-{4-[BIS(P-FLUOROPHENYL)METHYL]-1-PIPERAZINYL}-S-TRIAZINE
rxcui:528
chembl:CHEMBL1183717
chemidplus:27469-53-0
pubchem.compound:33887
drugbank:01430

Drug Info:

FDA Approval	not approved by the FDA
Drug Class	small molecule
Drug Indications	Respiratory Stimulant Agents
Drug Class	respiratory stimulant agents
Year of Approval	not approved by the fda

(0 More Sources)

Publications:

Rigoulet, 1990, Control processes in oxidative phosphorylation: kinetic constraints and stoichiometry., Biochim. Biophys. Acta
Rigoulet et al., 1989, Almitrine, a new kind of energy-transduction inhibitor acting on mitochondrial ATP synthase., Biochim. Biophys. Acta
Rigoulet et al., 1990, Flux-dependent increase in the stoichiometry of charge translocation by mitochondrial ATPase/ATP synthase induced by almitrine., Biochim. Biophys. Acta
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Benzi et al., 1993, Synaptosomal non-mitochondrial ATPase activities and drug treatment., Neurochem. Res.

ALMITRINE ATP1A1

Interaction Score: 41.22

Interaction Types & Directionality:

binder

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
2144185 2527061 2165421 11752352 8099718

Sources:
TdgClinicalTrial TEND TTD

TEND: ALMITRINE
- Version: 01-August-2011
Alternate Names:

ALMITRINE Primary Drug Name

Drug Info:

Year of Approval not approved by the fda

Drug Class respiratory stimulant agents

Publications:
TdgClinicalTrial: ALMITRINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Respiratory Stimulant Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Publications:
TTD: Almitrine
- Version: 2020.06.01
Alternate Names:

D0D9NA TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1183717
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications: