DGIdb - BARASERTIB Drug Record

BARASERTIB chembl:CHEMBL415049 Antineoplastic

Alternate Names:

AZD1152

BARASERTIB

AZD 1152

AZD-1152

Drug Info:

Drug Class Kinase Inhibitors

(0 More Sources)

Publications:

Cee VJ et al., 2010, Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor., J Med Chem

BARASERTIB AURKB

Interaction Score: 0.47

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Serine/threonine-protein kinase Aurora-B inhibitor

PMIDs:
20684549

Sources:
DTC MyCancerGenome ChemblInteractions
BARASERTIB FYN

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BARASERTIB AURKA

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
DTC
BARASERTIB LCK

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BARASERTIB KIT

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BARASERTIB RET

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BARASERTIB PDGFRA

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BARASERTIB PDGFRB

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BARASERTIB KDR

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

MyCancerGenome: BARASERTIB
- Version: 20-Jun-2017
Alternate Names:

AZD1152 Development Name

BARASERTIB Generic Name

Drug Info:

Drug Class Kinase Inhibitors

Publications:
DTC: BARASERTIB
- Version: 02-September-2020
Alternate Names:

CHEMBL415049 ChEMBL Drug ID

Drug Info:

Publications:

Cee VJ et al., 2010, Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor., J Med Chem
ChemblDrugs: chembl:CHEMBL415049
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL415049
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:

Direct Interaction	yes
Mechanism of Interaction	Serine/threonine-protein kinase Aurora-B inhibitor

AZD1152
BARASERTIB
AZD 1152
AZD-1152

AZD1152	Development Name
BARASERTIB	Generic Name

BARASERTIB Drug Record

BARASERTIB chembl:CHEMBL415049 Antineoplastic

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Serine/threonine-protein kinase Aurora-B inhibitor

PMIDs: 20684549

Sources: DTC MyCancerGenome ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

MyCancerGenome: BARASERTIB

Alternate Names: AZD1152 Development Name BARASERTIB Generic Name

Drug Info: Drug Class Kinase Inhibitors

Publications:

DTC: BARASERTIB

Alternate Names: CHEMBL415049 ChEMBL Drug ID

Drug Info:

Publications: Cee VJ et al., 2010, Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor., J Med Chem

ChemblDrugs: chembl:CHEMBL415049

Alternate Names:

Drug Info:

Publications:

ChemblInteractions: CHEMBL415049

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Serine/threonine-protein kinase Aurora-B inhibitor

PMIDs:
20684549

Sources:
DTC MyCancerGenome ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

AZD1152 Development Name

BARASERTIB Generic Name

Drug Info:

Drug Class Kinase Inhibitors

Alternate Names:

CHEMBL415049 ChEMBL Drug ID

Publications:

Cee VJ et al., 2010, Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor., J Med Chem