CABAZITAXEL Drug Record

  • CABAZITAXEL chembl:CHEMBL1201748 ApprovedAntineoplasticImmunotherapy

    Alternate Names:

    JEVTANA
    CABAZITAXEL
    TXD 258
    CABAZITAXEL ACETONATE
    TXD-258
    JEVTANA KIT
    XRP 6258
    XRP-6258
    TXD258
    XRP6258
    CABAZITAXELUM
    JEVANTA®
    TAXOID XRP6258
    chembl:CHEMBL1201748
    drugbank:06772
    pubchem.compound:9854073
    chemidplus:183133-96-2
    rxcui:996051

    Drug Info:

    FDA Approval approved
    Drug Class Small molecule
    Drug Indications antineoplastic agent
    Drug Class antineoplastic agent
    Year of Approval 2010
    (4 More Sources)

    Publications:

  • CABAZITAXEL   IGF2

    Interaction Score: 0.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25670080


    Sources:
    CIViC

  • CABAZITAXEL   TUB

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • CABAZITAXEL   TUBB1

    Interaction Score: 0.21

    Interaction Types & Directionality:
    binder
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name cabazitaxel, XRP6258,Jevtana
    Novel drug target Established target
    Mechanism of Interaction Tubulin inhibitor

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions TEND

  • CABAZITAXEL   TUBA4A

    Interaction Score: 0.18

    Interaction Types & Directionality:
    binder
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name cabazitaxel, XRP6258,Jevtana
    Novel drug target Established target
    Mechanism of Interaction Tubulin inhibitor

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • CABAZITAXEL   TUBB2B

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tubulin inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBA3E

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tubulin inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBB6

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Tubulin inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBA1C

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tubulin inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBB8

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Tubulin inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBA1B

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Tubulin inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBA3D

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tubulin inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBB3

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tubulin inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBB2A

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Tubulin inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBA1A

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tubulin inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBB4B

    Interaction Score: 0.08

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Tubulin inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   TUBB

    Interaction Score: 0.07

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tubulin inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CABAZITAXEL   CYP3A4

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB