DGIdb - CHLOROPROCAINE Drug Record

CHLOROPROCAINE chembl:CHEMBL1179047 Approved

Alternate Names:

CHLOROPROCAINE
CHLOROPROCAIN
CHLORPROCAINE
NESACAINE®
CHLOROPROCAINE HYDROCHLORIDE
CLOROPROCAINA
2-CHLOROPROCAINE
4-AMINO-2-CHLOROBENZOIC ACID 2-(DIETHYLAMINO)ETHYL ESTER
CHLOROPROCAINUM
chemidplus:133-16-4
chembl:CHEMBL1179047
drugbank:01161
rxcui:20859
pubchem.compound:8612

Drug Info:

Drug Class	anesthetics, local
Year of Approval	1955
FDA Approval	1955
Drug Class	small molecule
Drug Indications	Anesthetics, Local

(2 More Sources)

Publications:

Wong et al., 1993, On the mechanisms of potentiation of local anesthetics by bicarbonate buffer: drug structure-activity studies on isolated peripheral nerve., Anesth. Analg.
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

CHLOROPROCAINE CYB5R3

Interaction Score: 1.93

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
CHLOROPROCAINE ATP1A1

Interaction Score: 1.29

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
CHLOROPROCAINE SCN10A

Interaction Score: 1.02

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
8418714 17016423 17139284

Sources:
TdgClinicalTrial TEND
CHLOROPROCAINE G6PD

Interaction Score: 0.44

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB FDA

TEND: CHLOROPROCAINE
- Version: 01-August-2011
Alternate Names:

CHLOROPROCAINE Primary Drug Name

Drug Info:

Year of Approval 1955

Drug Class anesthetics, local

Publications:
TdgClinicalTrial: CHLOROPROCAINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Anesthetics, Local

Drug Class small molecule

FDA Approval 1955

Publications:
TTD: Chloroprocaine
- Version: 2020.06.01
Alternate Names:

D07NAJ TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1179047
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
PharmGKB: chloroprocaine
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:
FDA: Chloroprocaine
- Version: 04-September-2020
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target

CHLOROPROCAINE Drug Record

CHLOROPROCAINE chembl:CHEMBL1179047 Approved

Alternate Names:

Drug Info:

Publications:

CHLOROPROCAINE CYB5R3

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

CHLOROPROCAINE ATP1A1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

CHLOROPROCAINE SCN10A

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 8418714 17016423 17139284

Sources: TdgClinicalTrial TEND

CHLOROPROCAINE G6PD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB FDA

TEND: CHLOROPROCAINE

Alternate Names: CHLOROPROCAINE Primary Drug Name

Drug Info: Year of Approval 1955 Drug Class anesthetics, local

Publications:

TdgClinicalTrial: CHLOROPROCAINE

Alternate Names:

Drug Info: Drug Indications Anesthetics, Local Drug Class small molecule FDA Approval 1955

Publications:

TTD: Chloroprocaine

Alternate Names: D07NAJ TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1179047

Alternate Names:

Drug Info:

Publications:

PharmGKB: chloroprocaine

Alternate Names:

Drug Info:

Publications:

FDA: Chloroprocaine

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
8418714 17016423 17139284

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB FDA

Alternate Names:

CHLOROPROCAINE Primary Drug Name

Drug Info:

Year of Approval 1955

Drug Class anesthetics, local

Drug Info:

Drug Indications Anesthetics, Local

Drug Class small molecule

FDA Approval 1955

Alternate Names:

D07NAJ TTD Drug ID