DGIdb - CIXUTUMUMAB Drug Record

CIXUTUMUMAB chembl:CHEMBL1743001 Antineoplastic

Alternate Names:

NSC-742460
IMC-A12
CIXUTUMUMAB

Drug Info:

Drug Class	Therapeutic Antibodies
Pharmaceutical Developer	ImClone Systems
Source Reported Drug Name(s)	Cixutumumab/IMC-A12
Drug Class	Monoclonal Antibody
FDA Approval	not approved
Drug Class	antibody
Drug Indications	antineoplastic agent

(4 More Sources)

Publications:

Jiang et al., 2013, Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications., Oncotarget

CIXUTUMUMAB PTPRD

Interaction Score: 12.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23800680

Sources:
CIViC
CIXUTUMUMAB IGF1R

Interaction Score: 5.01

Interaction Types & Directionality:

antibody (inhibitory)

antagonist (inhibitory)

Interaction Info:

Trial Name cixutumumab, IMC-A12

Novel drug target Established target

Reported Cancer Type Prostate

PMIDs:
None found

Sources:
TALC MyCancerGenome TdgClinicalTrial ChemblInteractions CancerCommons TTD

MyCancerGenome: CIXUTUMUMAB
- Version: 20-Jun-2017
Alternate Names:

IMC-A12 Development Name

CIXUTUMUMAB Generic Name

Drug Info:

Drug Class Therapeutic Antibodies

Publications:
CancerCommons: CIXUTUMUMAB
- Version: 25-July-2013
Alternate Names:

Cixutumumab Drug Trade Name

IMC-A12 Drug Development Name

Drug Info:

Drug Class Monoclonal Antibody

Source Reported Drug Name(s) Cixutumumab/IMC-A12

Pharmaceutical Developer ImClone Systems

Publications:
TdgClinicalTrial: CIXUTUMUMAB
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications antineoplastic agent

Drug Class antibody

FDA Approval not approved

Publications:
CIViC: CIXUTUMUMAB
- Version: 14-September-2020
Alternate Names:

Drug Info:

Publications:

Jiang et al., 2013, Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications., Oncotarget
TALC: CIXUTUMUMAB
- Version: 12-May-2016
Alternate Names:

CIXUTUMUMAB Primary Drug Name

CIXUTUMUMAB Drug Generic Name

IMC-A12 Drug Synonym

Drug Info:

Publications:
TTD: Cixutumumab
- Version: 2020.06.01
Alternate Names:

D0E5DP TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1743001
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL1743001
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:

Trial Name	cixutumumab, IMC-A12
Novel drug target	Established target
Reported Cancer Type	Prostate

CIXUTUMUMAB	Primary Drug Name
CIXUTUMUMAB	Drug Generic Name
IMC-A12	Drug Synonym

antibody (inhibitory)
antagonist (inhibitory)

CIXUTUMUMAB Drug Record

CIXUTUMUMAB chembl:CHEMBL1743001 Antineoplastic

Alternate Names:

Drug Info:

Publications:

CIXUTUMUMAB PTPRD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23800680

Sources: CIViC

CIXUTUMUMAB IGF1R

Interaction Types & Directionality: antibody (inhibitory) antagonist (inhibitory)

Interaction Info: Trial Name cixutumumab, IMC-A12 Novel drug target Established target Reported Cancer Type Prostate

PMIDs: None found

Sources: TALC MyCancerGenome TdgClinicalTrial ChemblInteractions CancerCommons TTD

MyCancerGenome: CIXUTUMUMAB

Alternate Names: IMC-A12 Development Name CIXUTUMUMAB Generic Name

Drug Info: Drug Class Therapeutic Antibodies

Publications:

CancerCommons: CIXUTUMUMAB

Alternate Names: Cixutumumab Drug Trade Name IMC-A12 Drug Development Name

Drug Info: Drug Class Monoclonal Antibody Source Reported Drug Name(s) Cixutumumab/IMC-A12 Pharmaceutical Developer ImClone Systems

Publications:

TdgClinicalTrial: CIXUTUMUMAB

Alternate Names:

Drug Info: Drug Indications antineoplastic agent Drug Class antibody FDA Approval not approved

Publications:

CIViC: CIXUTUMUMAB

Alternate Names:

Drug Info:

Publications: Jiang et al., 2013, Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications., Oncotarget

TALC: CIXUTUMUMAB

Alternate Names: CIXUTUMUMAB Primary Drug Name CIXUTUMUMAB Drug Generic Name IMC-A12 Drug Synonym

Drug Info:

Publications:

TTD: Cixutumumab

Alternate Names: D0E5DP TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1743001

Alternate Names:

Drug Info:

Publications:

ChemblInteractions: CHEMBL1743001

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
23800680

Sources:
CIViC

Interaction Types & Directionality:

antibody (inhibitory)

antagonist (inhibitory)

Interaction Info:

Trial Name cixutumumab, IMC-A12

Novel drug target Established target

Reported Cancer Type Prostate

PMIDs:
None found

Sources:
TALC MyCancerGenome TdgClinicalTrial ChemblInteractions CancerCommons TTD

Alternate Names:

IMC-A12 Development Name

CIXUTUMUMAB Generic Name

Drug Info:

Drug Class Therapeutic Antibodies

Alternate Names:

Cixutumumab Drug Trade Name

IMC-A12 Drug Development Name

Drug Info:

Drug Class Monoclonal Antibody

Source Reported Drug Name(s) Cixutumumab/IMC-A12

Pharmaceutical Developer ImClone Systems

Drug Info:

Drug Indications antineoplastic agent

Drug Class antibody

FDA Approval not approved

Publications:

Jiang et al., 2013, Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications., Oncotarget

Alternate Names:

CIXUTUMUMAB Primary Drug Name

CIXUTUMUMAB Drug Generic Name

IMC-A12 Drug Synonym

Alternate Names:

D0E5DP TTD Drug ID