DGIdb - DOPAMINE Drug Record

DOPAMINE chembl:CHEMBL59 Approved

Alternate Names:

SINEMET
CARBILEV
NSC-173182
DOPAMINE
PARCOPA
INTROPIN
4-(2-AMINOETHYL)-PYROCATECHOL
3,4-DIHYDROXYPHENETHYLAMINE
DEOXYEPINEPHRINE
3-HYDROXYTYRAMINE
OXYTYRAMINE
4-(2-AMINOETHYL)PYROCATECHOL
4-(2-AMINOETHYL)BENZENE-1,2-DIOL
4-(2-AMINOETHYL)-1,2-BENZENEDIOL
DOPAMIN
HYDROXYTYRAMINE
ALPHA-(3,4-DIHYDROXYPHENYL)-BETA-AMINOETHANE
4-(2-AZANYLETHYL)BENZENE-1,2-DIOL
DYNATRA
4-(2-AMINOETHYL)CATECHOL
HYDROXYTYRAMIN
3,4-DIHYDROXYPHENYLETHYLAMINE
DOPHAMINE
DOPASTAT
REVIVAN
A-(3,4-DIHYDROXYPHENYL)-B-AMINOETHANE
DOPAMINA
DOPAMINUM
2-(3,4-DIHYDROXYPHENYL)ETHYLAMINE
drugbank:00988
chemidplus:51-61-6
chembl:CHEMBL59
pubchem.compound:681
rxcui:3628

Drug Info:

(0 More Sources)

Publications:

Hübner et al., 2000, Conjugated enynes as nonaromatic catechol bioisosteres: synthesis, binding experiments, and computational studies of novel dopamine receptor agonists recognizing preferentially the D(3) subtype., J. Med. Chem.
Dolzan et al., 2007, Polymorphisms in dopamine receptor DRD1 and DRD2 genes and psychopathological and extrapyramidal symptoms in patients on long-term antipsychotic treatment., Am. J. Med. Genet. B Neuropsychiatr. Genet.
Fu et al., 2007, Dopamine D1 receptor agonist and D2 receptor antagonist effects of the natural product (-)-stepholidine: molecular modeling and dynamics simulations., Biophys. J.
Ostadali et al., 2004, The Detection of Dopamine Gene Receptors (DRD1-DRD5) Expression on Human Peripheral Blood Lymphocytes by Real Time PCR., Iran J Allergy Asthma Immunol
Hoenicka et al., 2007, From dopaminergic genes to psychiatric disorders., Neurotox Res
da Silva Lobo et al., 2007, Dopamine genes and pathological gambling in discordant sib-pairs., J Gambl Stud
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Vilardaga JP et al., 2005, Molecular basis of inverse agonism in a G protein-coupled receptor., Nat Chem Biol

DOPAMINE DRD1

Interaction Score: 0.15

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

PMIDs:
10691700 17455212 17468175 17301410 17449449 17394052

Sources:
DTC
DOPAMINE ADRA2A

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16407989

Sources:
DTC PharmGKB
DOPAMINE ADRA1D

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
DOPAMINE ADRA2B

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
DOPAMINE DRD2

Interaction Score: 0.06

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

PMIDs:
17301410 11752352

Sources:
TTD
DOPAMINE ADRA1B

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
DOPAMINE ADRA2C

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
DOPAMINE ADRB1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
DOPAMINE ADRA1A

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
DOPAMINE MPHOSPH8

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOPAMINE HIF1A

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOPAMINE RECQL

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOPAMINE APEX1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOPAMINE FEN1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOPAMINE KDM4E

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOPAMINE TP53

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOPAMINE HSD17B10

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOPAMINE NFE2L2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOPAMINE EHMT2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

DTC: DOPAMINE
- Version: 02-September-2020
Alternate Names:

CHEMBL59 ChEMBL Drug ID

Drug Info:

Publications:

Vilardaga JP et al., 2005, Molecular basis of inverse agonism in a G protein-coupled receptor., Nat Chem Biol
TTD: Dopamine
- Version: 2020.06.01
Alternate Names:

D0T7OW TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL59
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
PharmGKB: dopamine
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

DOPAMINE Drug Record

DOPAMINE chembl:CHEMBL59 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: agonist (activating)

Interaction Info:

PMIDs: 10691700 17455212 17468175 17301410 17449449 17394052

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16407989

Sources: DTC PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: agonist (activating)

Interaction Info:

PMIDs: 17301410 11752352

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Interaction Types & Directionality:

agonist (activating)

PMIDs:
10691700 17455212 17468175 17301410 17449449 17394052

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
16407989

Sources:
DTC PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

agonist (activating)

PMIDs:
17301410 11752352

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

CHEMBL59 ChEMBL Drug ID

Publications:

Vilardaga JP et al., 2005, Molecular basis of inverse agonism in a G protein-coupled receptor., Nat Chem Biol

Alternate Names:

D0T7OW TTD Drug ID