DGIdb - FLUPIRTINE Drug Record

FLUPIRTINE chembl:CHEMBL255044

Alternate Names:

FLUPIRTINE

SID90341043

SID11111201

SID124880149

pubchem.compound:53276

rxcui:25193

drugbank:06623

chemidplus:56995-20-1

chembl:CHEMBL255044

Drug Info:

FDA Approval not approved

Drug Class Small molecule

Drug Indications analgesic

(1 More Sources)

Publications:

Nicoletti P et al., 2016, HLA-DRB1*16: 01-DQB1*05: 02 is a novel genetic risk factor for flupirtine-induced liver injury., Pharmacogenet Genomics

FLUPIRTINE KCNJ9

Interaction Score: 4.12

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name flupirtine,Effirma

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial
FLUPIRTINE KCNJ5

Interaction Score: 4.12

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name flupirtine,Effirma

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial
FLUPIRTINE KCNJ3

Interaction Score: 1.37

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name flupirtine,Effirma

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial
FLUPIRTINE KCNJ6

Interaction Score: 1.03

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name flupirtine,Effirma

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial
FLUPIRTINE HLA-DQB1

Interaction Score: 0.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26959717

Sources:
PharmGKB
FLUPIRTINE HLA-DRB1

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26959717

Sources:
PharmGKB
FLUPIRTINE EYA2

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUPIRTINE RGS4

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUPIRTINE HIF1A

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUPIRTINE CBX1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUPIRTINE HSD17B10

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUPIRTINE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUPIRTINE CYP2D6

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUPIRTINE EHMT2

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUPIRTINE CYP3A4

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

TdgClinicalTrial: FLUPIRTINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications analgesic

Drug Class Small molecule

FDA Approval not approved

Publications:
TTD: Flupirtine
- Version: 2020.06.01
Alternate Names:

D0SD9V TTD Drug ID

Drug Info:

Publications:

Morecroft I et al., 2009, Treatment with the Kv7 potassium channel activator flupirtine is beneficial in two independent mouse models of pulmonary hypertension., Br J Pharmacol
PharmGKB: flupirtine
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

Nicoletti P et al., 2016, HLA-DRB1*16: 01-DQB1*05: 02 is a novel genetic risk factor for flupirtine-induced liver injury., Pharmacogenet Genomics
DTC: FLUPIRTINE
- Version: 02-September-2020
Alternate Names:

CHEMBL255044 ChEMBL Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL255044
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

FDA Approval	not approved
Drug Class	Small molecule
Drug Indications	analgesic

FLUPIRTINE
SID90341043
SID11111201
SID124880149
pubchem.compound:53276
rxcui:25193
drugbank:06623
chemidplus:56995-20-1
chembl:CHEMBL255044

Trial Name	flupirtine,Effirma
Novel drug target	Novel Target

Trial Name	flupirtine,Effirma
Novel drug target	Novel Target

Trial Name	flupirtine,Effirma
Novel drug target	Novel Target

FLUPIRTINE Drug Record

FLUPIRTINE chembl:CHEMBL255044

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info: Trial Name flupirtine,Effirma Novel drug target Novel Target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Trial Name flupirtine,Effirma Novel drug target Novel Target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Trial Name flupirtine,Effirma Novel drug target Novel Target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Trial Name flupirtine,Effirma Novel drug target Novel Target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 26959717

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 26959717

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

TdgClinicalTrial: FLUPIRTINE

Alternate Names:

Drug Info: Drug Indications analgesic Drug Class Small molecule FDA Approval not approved

Publications:

TTD: Flupirtine

Alternate Names: D0SD9V TTD Drug ID

Drug Info:

Publications: Morecroft I et al., 2009, Treatment with the Kv7 potassium channel activator flupirtine is beneficial in two independent mouse models of pulmonary hypertension., Br J Pharmacol

PharmGKB: flupirtine

Alternate Names:

Drug Info:

Publications: Nicoletti P et al., 2016, HLA-DRB1*16: 01-DQB1*05: 02 is a novel genetic risk factor for flupirtine-induced liver injury., Pharmacogenet Genomics

DTC: FLUPIRTINE

Alternate Names: CHEMBL255044 ChEMBL Drug ID

Drug Info:

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name flupirtine,Effirma

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name flupirtine,Effirma

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name flupirtine,Effirma

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name flupirtine,Effirma

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

PMIDs:
26959717

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
26959717

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Drug Info:

Drug Indications analgesic

Drug Class Small molecule

FDA Approval not approved

Alternate Names:

D0SD9V TTD Drug ID

Publications:

Morecroft I et al., 2009, Treatment with the Kv7 potassium channel activator flupirtine is beneficial in two independent mouse models of pulmonary hypertension., Br J Pharmacol

Publications:

Nicoletti P et al., 2016, HLA-DRB116: 01-DQB105: 02 is a novel genetic risk factor for flupirtine-induced liver injury., Pharmacogenet Genomics

Alternate Names:

CHEMBL255044 ChEMBL Drug ID