LOXAPINE Drug Record

  • LOXAPINE   DRD2

    Interaction Score: 0.69

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Novel drug target Established target
    Trial Name AZ-004
    Mechanism of Interaction D2-like dopamine receptor antagonist

    PMIDs:
    9570468 6239298 15694653 8665533 9342550 11752352 8101879


    Sources:
    TdgClinicalTrial ChemblInteractions TEND TTD

  • LOXAPINE   HTR2C

    Interaction Score: 0.41

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serotonin 2c (5-HT2c) receptor antagonist
    Direct Interaction yes

    PMIDs:
    10991983


    Sources:
    ChemblInteractions

  • LOXAPINE   HTR2A

    Interaction Score: 0.31

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name AZ-004
    Novel drug target Established target
    Mechanism of Interaction Serotonin 2a (5-HT2a) receptor antagonist

    PMIDs:
    12664192


    Sources:
    TdgClinicalTrial ChemblInteractions

  • LOXAPINE   DRD4

    Interaction Score: 0.25

    Interaction Types & Directionality:
    binder
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction D2-like dopamine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • LOXAPINE   DRD1

    Interaction Score: 0.2

    Interaction Types & Directionality:
    binder
    antagonist (inhibitory)

    Interaction Info:

    PMIDs:
    11752352


    Sources:
    DTC TEND

  • LOXAPINE   DRD3

    Interaction Score: 0.16

    Interaction Types & Directionality:
    binder
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction D2-like dopamine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • TEND: LOXAPINE

    • Version: 01-August-2011

    Alternate Names:
    LOXAPINE Primary Drug Name

    Drug Info:
    Year of Approval 1975
    Drug Class antipsychotic agents

    Publications:

  • TdgClinicalTrial: LOXAPINE

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications antipsychotic agent
    Drug Class Small Molecule
    FDA Approval approved

    Publications:

  • DTC: LOXAPINE

    • Version: 02-September-2020

    Alternate Names:
    CHEMBL831 ChEMBL Drug ID

    Drug Info:

    Publications:

  • TTD: Loxapine

    • Version: 2020.06.01

    Alternate Names:
    D0U5OE TTD Drug ID

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL831

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL831

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications: