DGIdb - METHYLERGONOVINE Drug Record

METHYLERGONOVINE chembl:CHEMBL1201356 Approved

Alternate Names:

METHYLERGOMETRINE
METHYLERGONOVINE
METHERGINE®
METILERGOMETRINA
D-LYSERGIC ACID 1-BUTANOLAMIDE
METHYLERGOMETRINUM
MET827
METHYLERGOBASIN
MÉTHYLERGOMÉTRINE
METHYLERGOMETRIN
9,10-DIDEHYDRO-N-[1-(HYDROXYMETHYL)-PROPYL]-D-LYSERGAMIDE
ERGOTYL
pubchem.compound:8226
chemidplus:113-42-8
rxcui:6883
drugbank:00353
chembl:CHEMBL1201356

Drug Info:

Drug Class	abortifacient agents
Year of Approval	1946
FDA Approval	1946
Drug Class	small molecule
Drug Indications	Abortifacient Agents

(1 More Sources)

Publications:

Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Reyes et al., Reinforcement in an in vitro analog of appetitive classical conditioning of feeding behavior in Aplysia: blockade by a dopamine antagonist., Learn. Mem.
Nargeot et al., 1999, Dopaminergic synapses mediate neuronal changes in an analogue of operant conditioning., J. Neurophysiol.

METHYLERGONOVINE DRD1

Interaction Score: 0.59

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
11752352 17016423 17139284 15930499 10200235

Sources:
DTC TdgClinicalTrial TEND TTD
METHYLERGONOVINE RGS4

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLERGONOVINE RECQL

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLERGONOVINE ALDH1A1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLERGONOVINE VDR

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
METHYLERGONOVINE EHMT2

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

TEND: METHYLERGONOVINE
- Version: 01-August-2011
Alternate Names:

METHYLERGONOVINE Primary Drug Name

Drug Info:

Year of Approval 1946

Drug Class abortifacient agents

Publications:
TdgClinicalTrial: METHYLERGONOVINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Abortifacient Agents

Drug Class small molecule

FDA Approval 1946

Publications:
DTC: METHYLERGONOVINE
- Version: 02-September-2020
Alternate Names:

CHEMBL1201356 ChEMBL Drug ID

Drug Info:

Publications:
TTD: Methylergonovine
- Version: 2020.06.01
Alternate Names:

D05AHE TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1201356
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target

METHYLERGONOVINE Drug Record

METHYLERGONOVINE chembl:CHEMBL1201356 Approved

Alternate Names:

Drug Info:

Publications:

METHYLERGONOVINE DRD1

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 11752352 17016423 17139284 15930499 10200235

Sources: DTC TdgClinicalTrial TEND TTD

METHYLERGONOVINE RGS4

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

METHYLERGONOVINE RECQL

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

METHYLERGONOVINE ALDH1A1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

METHYLERGONOVINE VDR

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

METHYLERGONOVINE EHMT2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

TEND: METHYLERGONOVINE

Alternate Names: METHYLERGONOVINE Primary Drug Name

Drug Info: Year of Approval 1946 Drug Class abortifacient agents

Publications:

TdgClinicalTrial: METHYLERGONOVINE

Alternate Names:

Drug Info: Drug Indications Abortifacient Agents Drug Class small molecule FDA Approval 1946

Publications:

DTC: METHYLERGONOVINE

Alternate Names: CHEMBL1201356 ChEMBL Drug ID

Drug Info:

Publications:

TTD: Methylergonovine

Alternate Names: D05AHE TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1201356

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
11752352 17016423 17139284 15930499 10200235

Sources:
DTC TdgClinicalTrial TEND TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

METHYLERGONOVINE Primary Drug Name

Drug Info:

Year of Approval 1946

Drug Class abortifacient agents

Drug Info:

Drug Indications Abortifacient Agents

Drug Class small molecule

FDA Approval 1946

Alternate Names:

CHEMBL1201356 ChEMBL Drug ID

Alternate Names:

D05AHE TTD Drug ID