DGIdb - MICONAZOLE Drug Record

MICONAZOLE chembl:CHEMBL91 Approved

Alternate Names:

DERMAZOLE
CONOFITE
VUSION
MONISTAT-DERM
MONISTAT
MONISTAT-3
MICONAZOLE
DUMICOAT
ORAVIG
LORAMYC
MICATIN
NSC-170986

Drug Info:

(1 More Sources)

Publications:

Pasanen et al., 1988, Inhibition of human hepatic and placental xenobiotic monooxygenases by imidazole antimycotics., Biochem. Pharmacol.
Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev
Sakaeda et al., 2005, Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs., J. Pharm. Pharmacol.
Svecova L et al., 2008, Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression., Drug Metab Dispos

MICONAZOLE CYP3A7

Interaction Score: 1.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
3263862

Sources:
NCI
MICONAZOLE NR1I2

Interaction Score: 0.09

Interaction Types & Directionality:

partial agonist (activating)

Interaction Info:

PMIDs:
17998298

Sources:
PharmGKB
MICONAZOLE ABCB1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15969931

Sources:
NCI
MICONAZOLE HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MICONAZOLE CYP3A4

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9187528

Sources:
DTC PharmGKB
MICONAZOLE IDH1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MICONAZOLE CYP2C9

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MICONAZOLE KDM4A

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MICONAZOLE VDR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MICONAZOLE CYP2C19

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MICONAZOLE CYP1A2

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MICONAZOLE CYP2D6

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

NCI: MICONAZOLE

Version: 14-September-2017

Alternate Names:

C29257 NCI drug code

Drug Info:

Publications:

Pasanen et al., 1988, Inhibition of human hepatic and placental xenobiotic monooxygenases by imidazole antimycotics., Biochem. Pharmacol.

Sakaeda et al., 2005, Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs., J. Pharm. Pharmacol.

PharmGKB: miconazole
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev
DTC: MICONAZOLE
- Version: 02-September-2020
Alternate Names:

CHEMBL91 ChEMBL Drug ID

Drug Info:

Publications:
TTD: Miconazole
- Version: 2020.06.01
Alternate Names:

D00AXJ TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL91
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

MICONAZOLE Drug Record

MICONAZOLE chembl:CHEMBL91 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 3263862

Sources: NCI

Interaction Types & Directionality: partial agonist (activating)

Interaction Info:

PMIDs: 17998298

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15969931

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9187528

Sources: DTC PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

NCI: MICONAZOLE

Alternate Names: C29257 NCI drug code

Drug Info:

PharmGKB: miconazole

Alternate Names:

Drug Info:

Publications: Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev

DTC: MICONAZOLE

Alternate Names: CHEMBL91 ChEMBL Drug ID

Drug Info:

Publications:

TTD: Miconazole

Alternate Names: D00AXJ TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL91

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
3263862

Sources:
NCI

Interaction Types & Directionality:

partial agonist (activating)

PMIDs:
17998298

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
15969931

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
9187528

Sources:
DTC PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

C29257 NCI drug code

Publications:

Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev

Alternate Names:

CHEMBL91 ChEMBL Drug ID

Alternate Names:

D00AXJ TTD Drug ID