DGIdb - NORGESTREL Drug Record

NORGESTREL chembl:CHEMBL2107797 Approved

Alternate Names:

OPILL
PREVIFEM
WY-3707
NORGESTREL
TRI-PREVIFEM
PREFEST
OVRETTE
SPRINTEC
TRI-SPRINTEC

Drug Info:

FDA Approval	Approved before 1982
Drug Class	small molecule
Drug Indications	Contraceptives, Oral, Synthetic
Year of Approval	approved before 1982
Drug Class	contraceptives, oral, synthetic

(2 More Sources)

Publications:

Kloosterboer et al., 1988, Selectivity in progesterone and androgen receptor binding of progestagens used in oral contraceptives., Contraception
Hammond et al., 2001, Preclinical profiles of progestins used in formulations of oral contraceptives and hormone replacement therapy., Am. J. Obstet. Gynecol.
Miller et al., 1979, Some estrogenic effects of two oral contraceptives consisting of norgestrel and two different doses of ethynylestradiol., Contraception

NORGESTREL SHBG

Interaction Score: 4.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
573191

Sources:
NCI
NORGESTREL PGR

Interaction Score: 0.81

Interaction Types & Directionality:

agonist (activating)

binder

Interaction Info:

Trial Name -

Novel drug target Established target

Mechanism of Interaction Progesterone receptor agonist

PMIDs:
11521119

Sources:
TdgClinicalTrial ChemblInteractions TEND
NORGESTREL HSPA5

Interaction Score: 0.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NORGESTREL ESR1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TEND
NORGESTREL AR

Interaction Score: 0.02

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

PMIDs:
3139361

Sources:
DTC
NORGESTREL NFE2L2

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

TEND: NORGESTREL
- Version: 01-August-2011
Alternate Names:

NORGESTREL Primary Drug Name

Drug Info:

Drug Class contraceptives, oral, synthetic

Year of Approval approved before 1982

Publications:
TdgClinicalTrial: NORGESTREL
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Contraceptives, Oral, Synthetic

Drug Class small molecule

FDA Approval Approved before 1982

Publications:
NCI: NORGESTREL
- Version: 14-September-2017
Alternate Names:

C703 NCI drug code

Drug Info:

Publications:

Miller et al., 1979, Some estrogenic effects of two oral contraceptives consisting of norgestrel and two different doses of ethynylestradiol., Contraception
DTC: NORGESTREL
- Version: 02-September-2020
Alternate Names:

CHEMBL2107797 ChEMBL Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL2107797
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL2107797
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target
Mechanism of Interaction	Progesterone receptor agonist

agonist (activating)
binder

NORGESTREL Drug Record

NORGESTREL chembl:CHEMBL2107797 Approved

Alternate Names:

Drug Info:

Publications:

NORGESTREL SHBG

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 573191

Sources: NCI

NORGESTREL PGR

Interaction Types & Directionality: agonist (activating) binder

Interaction Info: Trial Name - Novel drug target Established target Mechanism of Interaction Progesterone receptor agonist

PMIDs: 11521119

Sources: TdgClinicalTrial ChemblInteractions TEND

NORGESTREL HSPA5

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

NORGESTREL ESR1

Interaction Types & Directionality: n/a

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: None found

Sources: TdgClinicalTrial TEND

NORGESTREL AR

Interaction Types & Directionality: agonist (activating)

Interaction Info:

PMIDs: 3139361

Sources: DTC

NORGESTREL NFE2L2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

TEND: NORGESTREL

Alternate Names: NORGESTREL Primary Drug Name

Drug Info: Drug Class contraceptives, oral, synthetic Year of Approval approved before 1982

Publications:

TdgClinicalTrial: NORGESTREL

Alternate Names:

Drug Info: Drug Indications Contraceptives, Oral, Synthetic Drug Class small molecule FDA Approval Approved before 1982

Publications:

NCI: NORGESTREL

Alternate Names: C703 NCI drug code

Drug Info:

Publications: Miller et al., 1979, Some estrogenic effects of two oral contraceptives consisting of norgestrel and two different doses of ethynylestradiol., Contraception

DTC: NORGESTREL

Alternate Names: CHEMBL2107797 ChEMBL Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL2107797

Alternate Names:

Drug Info:

Publications:

ChemblInteractions: CHEMBL2107797

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
573191

Sources:
NCI

Interaction Types & Directionality:

agonist (activating)

binder

Interaction Info:

Trial Name -

Novel drug target Established target

Mechanism of Interaction Progesterone receptor agonist

PMIDs:
11521119

Sources:
TdgClinicalTrial ChemblInteractions TEND

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

agonist (activating)

PMIDs:
3139361

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

NORGESTREL Primary Drug Name

Drug Info:

Drug Class contraceptives, oral, synthetic

Year of Approval approved before 1982

Drug Info:

Drug Indications Contraceptives, Oral, Synthetic

Drug Class small molecule

FDA Approval Approved before 1982

Alternate Names:

C703 NCI drug code

Publications:

Miller et al., 1979, Some estrogenic effects of two oral contraceptives consisting of norgestrel and two different doses of ethynylestradiol., Contraception

Alternate Names:

CHEMBL2107797 ChEMBL Drug ID