43 |
ACETYLCHOLINESTERASE (CARTWRIGHT BLOOD GROUP) |
ACHE |
ACEE |
ARACHE |
N-ACHE |
YT |
100740 |
108 |
ENSG00000087085 |
OTTHUMG00000157033 |
P22303 |
ACES_HUMAN |
acetylcholinesterase |
ACETYLCHOLINESTERASE PRECURSOR (EC 3.1.1.7) (ACHE). [SOURCE:UNIPROT/SWISSPROT;ACC:P22303] |
PA20 |
T30082 |
Interpro Acc | IPR002018 |
Interpro Name | Carboxylesterase, type B |
Uniprot Status | Swiss-Prot |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Domain |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Short Name | CarbesteraseB |
Target Main Class | Enzymes |
Target Subclass | 3.1.1.7 |
Target Class | Enzymes |
Target Subclass | EC:3.1.1.7 |
Gene Biotype | PROTEIN_CODING |
CELL SURFACE |
DRUGGABLE GENOME |
inhibitor (inhibitory) |
Mechanism of Interaction | Cholinesterases; ACHE & BCHE inhibitor |
Direct Interaction | yes |
Trial Name | rivastigmine,Exelon |
inhibitor (inhibitory) |
Trial Name | galantamine hydrobromide,Razadyne, Reminyl |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Acetylcholinesterase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Acetylcholinesterase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Acetylcholinesterase inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Acetylcholinesterase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Acetylcholinesterase inhibitor |
Direct Interaction | yes |
activator (activating) |
Mechanism of Interaction | Acetylcholinesterase activator |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Acetylcholinesterase inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Acetylcholinesterase inhibitor |
Direct Interaction | yes |
n/a |
Trial Name | acotiamide hydrochloride, YM-443, Z-338 |
Novel drug target | Established target |
n/a |
Novel drug target | Established target |
Trial Name | Phenserine |
inhibitor (inhibitory) |
Trial Name | itopride,Itax |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Acetylcholinesterase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Cholinesterases; ACHE & BCHE inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Cholinesterases; ACHE & BCHE inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Acetylcholinesterase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Acetylcholinesterase inhibitor |
n/a |
Novel drug target | Established target |
Trial Name | Dimebon |
ACHE | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
ENSG00000087085 | Ensembl Gene Id |
ACHE | Display Id |
ACETYLCHOLINESTERASE PRECURSOR (EC 3.1.1.7) (ACHE). [SOURCE:UNIPROT/SWISSPROT;ACC:P22303] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
P22303 | Uniprot Accession |
ENSG00000087085 | Ensembl Gene Id |
43 | Entrez Gene Id |
Target Main Class | Enzymes |
Target Subclass | 3.1.1.7 |
ACHE | Uniprot Gene Name |
43 | Entrez Gene Id |
P22303 | Uniprot Accession |
Interpro Acc | IPR002018 |
Interpro Name | Carboxylesterase, type B |
Uniprot Status | Swiss-Prot |
DRUGGABLE GENOME |
ACHE | Gene Symbol |
Target Subclass | EC:3.1.1.7 |
Target Class | Enzymes |
PA20 | PharmGKB ID |
ENSG00000087085 | Gene Symbol |
ACHE | Ensembl Id |
DRUGGABLE GENOME |
ACHE | GENE_SYMBOL |
Acetylcholinesterase | UNIPROT |
AChE | UNIPROT |
AChE | TTD Gene Abbreviation |
T30082 | TTD Target ID |
CELL SURFACE |