185 |
ANGIOTENSIN II RECEPTOR TYPE 1 |
AGTR1 |
AG2S |
AGTR1B |
AT1 |
AT1AR |
AT1B |
AT1BR |
AT1R |
AT2R1 |
HAT1R |
106165 |
336 |
ENSG00000144891 |
OTTHUMG00000159503 |
P30556 |
AGTR1_HUMAN |
AGTR1A |
AT2R1B |
Type-1 angiotensin II receptor |
Angiotensin II type-1 receptor |
TYPE-1 ANGIOTENSIN II RECEPTOR (AT1) (AT1AR). [SOURCE:UNIPROT/SWISSPROT;ACC:P30556] |
PA43 |
Angiotensin II receptor type-1 |
T74456 |
AT2R1A |
Transmembrane Helix Count | 7 |
Target Subclass | Rhodopsin |
Target Subclass | GPCR |
Target Main Class | Receptors |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
Human Readable Name | DRUGGABLE GENOME |
Interpro Acc | IPR000276 |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Interpro Name | GPCR, rhodopsin-like, 7TM |
Uniprot Status | Swiss-Prot |
Interpro Type | Family |
Uniprot Evidence | 1: Evidence at protein level |
Target Class | Receptors |
Gene Biotype | PROTEIN_CODING |
G PROTEIN COUPLED RECEPTOR |
DRUGGABLE GENOME |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | valsartan,Diovan |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
Trial Name | CS-8663, amlodipine + olmesartan,Azor, Sevikar |
antagonist (inhibitory) |
Trial Name | azilsartan medoxomil, TAK-491 |
Novel drug target | Established target |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
antagonist (inhibitory) |
Trial Name | telmisartan,Micardis, Micardis HCT |
Novel drug target | Established target |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
antagonist (inhibitory) |
Trial Name | candesartan cilexetil,Atacand |
Novel drug target | Established target |
antagonist (inhibitory) |
Trial Name | irbesartan,Avapro, Irbetan |
Novel drug target | Established target |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Type-1 angiotensin II receptor antagonist |
Direct Interaction | yes |
AGTR1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
P30556 | Uniprot Accession |
185 | Entrez Gene Id |
AGTR1_HUMAN | Uniprot Id |
Transmembrane Helix Count | 7 |
Target Subclass | Rhodopsin |
Target Subclass | GPCR |
TYPE-1 ANGIOTENSIN II RECEPTOR | Uniprot Protein Name |
185 | Entrez Gene Id |
AGTR1 | Uniprot Gene Name |
Interpro Acc | IPR000276 |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME |
AGTR1 | Display Id |
ENSG00000144891 | Ensembl Gene Id |
TYPE-1 ANGIOTENSIN II RECEPTOR (AT1) (AT1AR). [SOURCE:UNIPROT/SWISSPROT;ACC:P30556] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
AGTR1 | Gene Symbol |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
PA43 | PharmGKB ID |
ENSG00000144891 | Gene Symbol |
AGTR1 | Ensembl Id |
DRUGGABLE GENOME |
AGTR1B | GENE_SYMBOL |
AT2R1 | GENE_SYMBOL |
AT2R1B | GENE_SYMBOL |
AGTR1A | GO Gene Synonym |
AGTR1B | GO Gene Synonym |
AT2R1 | GO Gene Synonym |
G PROTEIN COUPLED RECEPTOR |
185 | Gene ID |
AG2S | dGene Synonym |
AGTR1A | dGene Synonym |
G PROTEIN COUPLED RECEPTOR |
AGTR1 | TTD Gene Abbreviation |
T74456 | TTD Target ID |