2932 |
GLYCOGEN SYNTHASE KINASE 3 BETA |
GSK3B |
605004 |
4617 |
ENSG00000082701 |
OTTHUMG00000133765 |
P49841 |
GSK3B_HUMAN |
GLYCOGEN SYNTHASE KINASE-3 BETA |
GSK-3 beta |
Serine/threonine-protein kinase GSK3B |
GLYCOGEN SYNTHASE KINASE-3 BETA (EC 2.7.1.37) (GSK-3 BETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P49841] |
PA29009 |
GSK-3B |
T70977 |
- |
Target Class | Enzymes |
Target Subclass | EC:2.7.11.26 |
Uniprot Status | Swiss-Prot |
Interpro Short Name | Ser/Thr_dual-sp_kinase_dom |
Human Readable Name | DRUGGABLE GENOME |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Type | Domain |
Human Readable Name | KINASE |
Interpro Name | Serine/threonine- / dual-specificity protein kinase, catalytic domain |
Interpro Acc | IPR002290 |
Gene Biotype | PROTEIN_CODING |
KINASE |
SERINE THREONINE KINASE |
DRUGGABLE GENOME |
CLINICALLY ACTIONABLE |
TRANSCRIPTION FACTOR |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glycogen synthase kinase-3 beta inhibitor |
Trial Name | tideglusib, NP-12,Nypta |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glycogen synthase kinase-3 inhibitor |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glycogen synthase kinase-3 inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Glycogen synthase kinase-3 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Glycogen synthase kinase-3 beta inhibitor |
Direct Interaction | yes |
GSK3B | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
GSK3B | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:2.7.11.26 |
ENSG00000082701 | Ensembl Gene Id |
GLYCOGEN SYNTHASE KINASE-3 BETA (EC 2.7.1.37) (GSK-3 BETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P49841] | Description |
GSK3B | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
P49841 | Uniprot Accession |
2932 | Entrez Gene Id |
GSK3B_HUMAN | Uniprot Id |
Uniprot Status | Swiss-Prot |
Interpro Short Name | Ser/Thr_dual-sp_kinase_dom |
Human Readable Name | DRUGGABLE GENOME |
KINASE, DRUGGABLE GENOME |
PA29009 | PharmGKB ID |
GSK3B | Gene Symbol |
GSK3B | GENE_SYMBOL |
Glycogen synthase kinase-3 beta | UNIPROT |
Serine/threonine-protein kinase GSK3B | UNIPROT |
ENSG00000082701 | Gene Symbol |
GSK3B | Ensembl Id |
DRUGGABLE GENOME |
2932 | Gene ID |
- | dGene Synonym |
KINASE, SERINE THREONINE KINASE |
GSK-3B | TTD Gene Abbreviation |
T70977 | TTD Target ID |
Glycogen synthase kinase-3 beta | Gene Name |
P49841 | UniProt ID |
KINASE, TRANSCRIPTION FACTOR |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |
KINASE, SERINE THREONINE KINASE |