AT-9283 Drug Record

  • AT-9283 chembl:CHEMBL495727 Antineoplastic

    Alternate Names:

    AT-9283
    AT9283
    AT 9283

    Drug Info:

    FDA Approval not approved
    Drug Class Small molecule
    Drug Indications antineoplastic agent
    Drug Class Kinase Inhibitors
    (2 More Sources)

    Publications:

  • AT-9283   AURKA

    Interaction Score: 0.6

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora-A inhibitor

    PMIDs:
    None found


    Sources:
    TALC MyCancerGenome TdgClinicalTrial ChemblInteractions TTD

  • AT-9283   AURKB

    Interaction Score: 0.48

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Serine/threonine-protein kinase Aurora-B inhibitor
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TALC MyCancerGenome TdgClinicalTrial ChemblInteractions TTD

  • AT-9283   JAK3

    Interaction Score: 0.35

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase JAK3 inhibitor
    Direct Interaction yes
    Notes

    PMIDs:
    None found


    Sources:
    TALC ChemblInteractions

  • AT-9283   TYK2

    Interaction Score: 0.28

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes

    PMIDs:
    None found


    Sources:
    TALC

  • AT-9283   JAK2

    Interaction Score: 0.27

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase JAK2 inhibitor
    Direct Interaction yes
    Notes

    PMIDs:
    None found


    Sources:
    TALC MyCancerGenome ChemblInteractions

  • AT-9283   ABL1

    Interaction Score: 0.17

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Tyrosine-protein kinase ABL inhibitor

    PMIDs:
    None found


    Sources:
    MyCancerGenome ChemblInteractions

  • AT-9283   RPS6KA3

    Interaction Score: 0.17

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes

    PMIDs:
    None found


    Sources:
    TALC

  • AT-9283   GSK3B

    Interaction Score: 0.12

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes

    PMIDs:
    None found


    Sources:
    TALC

  • AT-9283   RET

    Interaction Score: 0.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes

    PMIDs:
    None found


    Sources:
    TALC

  • AT-9283   FLT3

    Interaction Score: 0.07

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Tyrosine-protein kinase receptor FLT3 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • AT-9283   YES1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes

    PMIDs:
    None found


    Sources:
    TALC

  • MyCancerGenome: AT9283

    • Version: 20-Jun-2017

    Alternate Names:
    AT9283 Development Name

    Drug Info:
    Drug Class Kinase Inhibitors

    Publications:

  • TdgClinicalTrial: AT9283

    • Version: January-2014

    Alternate Names:

    Drug Info:
    Drug Indications antineoplastic agent
    Drug Class Small molecule
    FDA Approval not approved

    Publications:

  • TTD: AT9283

    • Version: 2020.06.01

    Alternate Names:
    D05PZB TTD Drug ID

    Drug Info:

    Publications:

  • TALC: AT9283

    • Version: 12-May-2016

    Alternate Names:
    AT9283 Primary Drug Name
    AT9283 Drug Synonym

    Drug Info:

    Publications:

  • ChemblDrugs: chembl:CHEMBL495727

    • Version: ChEMBL_27

    Alternate Names:

    Drug Info:

    Publications:

  • ChemblInteractions: CHEMBL495727

    • Version: chembl_23

    Alternate Names:

    Drug Info:

    Publications: