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POLE 5426 Druggable GenomeClinically Actionable
Alternate Names:
5426 DNA POLYMERASE EPSILON, CATALYTIC SUBUNIT POLE CRCS12 FILS POLE1 174762 9177 ENSG00000177084 OTTHUMG00000168045 Q07864 DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A DPOE1_HUMAN 4386 DNA POLYMERASE EPSILON, CATALYTIC SUBUNIT A (EC 2.7.7.7) (DNA POLYMERASE II SUBUNIT A). [SOURCE:UNIPROT/SWISSPROT;ACC:Q07864] DNA polymerase II subunit A IMAGEI Gene Info:
Interpro Name DNA-directed DNA polymerase, family B Uniprot Status Swiss-Prot Interpro Acc IPR006134 Human Readable Name DRUGGABLE GENOME Human Readable Name DNA DIRECTED DNA POLYMERASE Interpro Type Family Interpro Name DNA-directed DNA polymerase, family B, exonuclease domain Interpro Short Name DNA-dir_DNA_pol_B Interpro Short Name DNA-dir_DNA_pol_B_multi_dom Uniprot Evidence 1: Evidence at protein level Interpro Acc IPR006133 Interpro Short Name DNA-dir_DNA_pol_B_exonuc Interpro Name DNA-directed DNA polymerase, family B, multifunctional domain Interpro Type Domain Interpro Acc IPR006172 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
DRUGGABLE GENOME DNA DIRECTED RNA POLYMERASE CLINICALLY ACTIONABLE ENZYME Publications:
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Interaction Score: 2.25
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Interaction Score: 2.06
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction DNA polymerase (alpha/delta/epsilon) inhibitor Direct Interaction yes -
Interaction Score: 1.77
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction DNA polymerase (alpha/delta/epsilon) inhibitor Direct Interaction yes -
Interaction Score: 1.37
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction DNA polymerase (alpha/delta/epsilon) inhibitor Direct Interaction yes -
Interaction Score: 0.29
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction DNA polymerase (alpha/delta/epsilon) inhibitor
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- Version: 101_38
Alternate Names:
POLE Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 26-July-2011
Alternate Names:
POLE Display Id ENSG00000177084 Ensembl Gene Id DNA POLYMERASE EPSILON, CATALYTIC SUBUNIT A (EC 2.7.7.7) (DNA POLYMERASE II SUBUNIT A). [SOURCE:UNIPROT/SWISSPROT;ACC:Q07864] Description Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 11-September-2012
Alternate Names:
5426 Entrez Gene Id DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A Uniprot Protein Name Q07864 Uniprot Accession Gene Info:
Interpro Name DNA-directed DNA polymerase, family B Uniprot Status Swiss-Prot Interpro Acc IPR006134 Gene Categories:
DNA DIRECTED RNA POLYMERASE Publications:
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Alternate Names:
5426 Entrez Gene ID 4386 CIViC Gene ID Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000177084 Gene Symbol POLE Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
POLE1 GENE_SYMBOL POLE GENE_SYMBOL DNA polymerase epsilon catalytic subunit A UNIPROT Gene Info:
Publications:
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Alternate Names:
POLE Gene Symbol Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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Alternate Names:
DNA polymerase epsilon catalytic subunit A Gene Name Q07864 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications:
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Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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- Version: 03-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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- Version: 04-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications: