PRKCH Gene Record

  • PRKCH 5583 Druggable Genome

    Alternate Names:

    5583
    PROTEIN KINASE C ETA
    PRKCH
    PKC-L
    PKCL
    PRKCL
    nPKC-eta
    605437
    9403
    ENSG00000027075
    OTTHUMG00000152341
    PKC
    P24723
    KPCL_HUMAN
    PROTEIN KINASE C ETA TYPE
    PROTEIN KINASE C, ETA TYPE (EC 2.7.1.-) (NPKC-ETA) (PKC-L). [SOURCE:UNIPROT/SWISSPROT;ACC:P24723]

    Gene Info:

    Uniprot Status Swiss-Prot
    Interpro Acc IPR002290
    Human Readable Name KINASE
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Target Class Enzymes
    Target Subclass EC:2.7.11.13
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • BRYOSTATIN   PRKCH

    Interaction Score: 0.74

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Bryostatin
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • GSK-690693   PRKCH

    Interaction Score: 0.52

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • CEP-2563   PRKCH

    Interaction Score: 0.52

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Protein kinase C (PKC) inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • UCN-01   PRKCH

    Interaction Score: 0.44

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • MIDOSTAURIN   PRKCH

    Interaction Score: 0.35

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • SOTRASTAURIN   PRKCH

    Interaction Score: 0.15

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Protein kinase C (PKC) inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • QUERCETIN   PRKCH

    Interaction Score: 0.11

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Ensembl: ENSG00000027075

    • Version: 101_38

    Alternate Names:
    PRKCH Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P24723

    • Version: 11-September-2012

    Alternate Names:
    PRKCH Uniprot Gene Name
    KPCL_HUMAN Uniprot Id
    P24723 Uniprot Accession

    Gene Info:
    Interpro Acc IPR002290
    Human Readable Name KINASE
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000027075

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000027075 Ensembl Gene Id
    PROTEIN KINASE C, ETA TYPE (EC 2.7.1.-) (NPKC-ETA) (PKC-L). [SOURCE:UNIPROT/SWISSPROT;ACC:P24723] Description
    PRKCH Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: P24723

    • Version: January-2014

    Alternate Names:
    PRKCH Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.13

    Publications:

  • MyCancerGenome: PRKCH

    • Version: 20-Jun-2017

    Alternate Names:
    5583 Entrez Gene Id
    PRKCH MyCancerGenome Gene Symbol
    PKC MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000027075

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000027075 Gene Symbol
    PRKCH Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: PKCL

    • Version: chembl_23

    Alternate Names:
    PRKCL GENE_SYMBOL
    PRKCH GENE_SYMBOL
    Protein kinase C eta type UNIPROT

    Gene Info:

    Publications:

  • HumanProteinAtlas: PRKCH

    • Version: 19.3

    Alternate Names:
    ENSG00000027075 Ensembl Gene ID
    PKC-L Human Protein Atlas Gene Synonym
    PKCL Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • GO: PRKCH

    • Version: 01-February-2022

    Alternate Names:
    PKCL GO Gene Synonym
    PRKCL GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • dGene: PRKCH

    • Version: 27-Jun-2013

    Alternate Names:
    5583 Gene ID
    PKC-L dGene Synonym
    PKCL dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • Pharos: PRKCH

    • Version: 01-February-2022

    Alternate Names:
    Protein kinase C eta type Gene Name
    P24723 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: