DGIdb - BRYOSTATIN Drug Record

BRYOSTATIN chembl:CHEMBL449158 Antineoplastic

Alternate Names:

BRYOSTATIN
BRYOSTATIN 1

Drug Info:

FDA Approval	not approved
Drug Class	Small molecule
Drug Indications	for treatment of alzheimer's disease

(1 More Sources)

Publications:

Keck GE et al., 2012, Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity., Bioorg Med Chem Lett
Kos et al., 2000, Protective role of IL-2 during activation of T cells with bryostatin 1., Int. J. Immunopharmacol.

BRYOSTATIN PRRT2

Interaction Score: 5.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenomeClinicalTrial
BRYOSTATIN PRKCB

Interaction Score: 1.19

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
22579485

Sources:
DTC TdgClinicalTrial
BRYOSTATIN PRKCA

Interaction Score: 0.81

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
22579485

Sources:
DTC TdgClinicalTrial
BRYOSTATIN PRKCH

Interaction Score: 0.74

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial
BRYOSTATIN PRKD1

Interaction Score: 0.57

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial
BRYOSTATIN PRKCD

Interaction Score: 0.52

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
22579485

Sources:
DTC TdgClinicalTrial
BRYOSTATIN PRKCE

Interaction Score: 0.43

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial
BRYOSTATIN IL2RA

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10988359

Sources:
NCI
BRYOSTATIN PRKCQ

Interaction Score: 0.3

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial
BRYOSTATIN PRKCG

Interaction Score: 0.25

Interaction Types & Directionality:

n/a

Interaction Info:

Novel drug target Established target

Trial Name Bryostatin

PMIDs:
None found

Sources:
TdgClinicalTrial
BRYOSTATIN PRKD2

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial
BRYOSTATIN PRKD3

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

Novel drug target Novel Target

Trial Name Bryostatin

PMIDs:
None found

Sources:
TdgClinicalTrial

TdgClinicalTrial: BRYOSTATIN
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications for treatment of alzheimer's disease

Drug Class Small molecule

FDA Approval not approved

Publications:
NCI: BRYOSTATIN
- Version: 14-September-2017
Alternate Names:

C1026 NCI drug code

Drug Info:

Publications:

Kos et al., 2000, Protective role of IL-2 during activation of T cells with bryostatin 1., Int. J. Immunopharmacol.
DTC: BRYOSTATIN
- Version: 02-September-2020
Alternate Names:

CHEMBL449158 ChEMBL Drug ID

Drug Info:

Publications:

Keck GE et al., 2012, Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity., Bioorg Med Chem Lett
ChemblDrugs: chembl:CHEMBL449158
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
MyCancerGenomeClinicalTrial: BRYOSTATIN
- Version: 30-February-2014
Alternate Names:

Drug Info:

Publications:

Trial Name	Bryostatin
Novel drug target	Established target

Trial Name	Bryostatin
Novel drug target	Established target

Trial Name	Bryostatin
Novel drug target	Established target

Trial Name	Bryostatin
Novel drug target	Novel Target

BRYOSTATIN Drug Record

BRYOSTATIN chembl:CHEMBL449158 Antineoplastic

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: MyCancerGenomeClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Trial Name Bryostatin Novel drug target Established target

PMIDs: 22579485

Sources: DTC TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Trial Name Bryostatin Novel drug target Established target

PMIDs: 22579485

Sources: DTC TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Trial Name Bryostatin Novel drug target Established target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Trial Name Bryostatin Novel drug target Novel Target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Trial Name Bryostatin Novel drug target Established target

PMIDs: 22579485

Sources: DTC TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Trial Name Bryostatin Novel drug target Established target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10988359

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info: Trial Name Bryostatin Novel drug target Established target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Novel drug target Established target Trial Name Bryostatin

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Trial Name Bryostatin Novel drug target Novel Target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info: Novel drug target Novel Target Trial Name Bryostatin

PMIDs: None found

Sources: TdgClinicalTrial

TdgClinicalTrial: BRYOSTATIN

Alternate Names:

Drug Info: Drug Indications for treatment of alzheimer's disease Drug Class Small molecule FDA Approval not approved

Publications:

NCI: BRYOSTATIN

Alternate Names: C1026 NCI drug code

Drug Info:

Publications: Kos et al., 2000, Protective role of IL-2 during activation of T cells with bryostatin 1., Int. J. Immunopharmacol.

DTC: BRYOSTATIN

Alternate Names: CHEMBL449158 ChEMBL Drug ID

Drug Info:

Publications: Keck GE et al., 2012, Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity., Bioorg Med Chem Lett

ChemblDrugs: chembl:CHEMBL449158

Alternate Names:

Drug Info:

Publications:

MyCancerGenomeClinicalTrial: BRYOSTATIN

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
22579485

Sources:
DTC TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
22579485

Sources:
DTC TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
22579485

Sources:
DTC TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

PMIDs:
10988359

Sources:
NCI

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Novel drug target Established target

Trial Name Bryostatin

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Bryostatin

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

Interaction Info:

Novel drug target Novel Target

Trial Name Bryostatin

PMIDs:
None found

Sources:
TdgClinicalTrial

Drug Info:

Drug Indications for treatment of alzheimer's disease

Drug Class Small molecule

FDA Approval not approved

Alternate Names:

C1026 NCI drug code

Publications:

Kos et al., 2000, Protective role of IL-2 during activation of T cells with bryostatin 1., Int. J. Immunopharmacol.

Alternate Names:

CHEMBL449158 ChEMBL Drug ID

Publications:

Keck GE et al., 2012, Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity., Bioorg Med Chem Lett