DGIdb - ANISINDIONE Drug Record

ANISINDIONE chembl:CHEMBL712 Approved

Alternate Names:

MIRADON
ANISINDIONE
2-(4-METHOXYPHENYL)INDAN-1,3-DIONE
MIRADON®
2-(4-METHOXYPHENYL)-1H-INDENE-1,3(2H)-DIONE
2-P-ANISYL-1,3-INDANDIONE
ANISINDIONUM
2-(P-METHOXYPHENYL)-1,3-INDANDIONE
2-(P-METHOXYPHENYL)INDANE-1,3-DIONE
ANISIN INDANDIONE
2-PARA-ANISYL-1,3-INDANDIONE
ANISINDIONA
rxcui:17941
chemidplus:117-37-3
drugbank:01125
pubchem.compound:2197
chembl:CHEMBL712

Drug Info:

Drug Class	anticoagulants
Year of Approval	1957
FDA Approval	1957
Drug Class	small molecule
Drug Indications	Anticoagulants

(2 More Sources)

Publications:

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.

ANISINDIONE GGCX

Interaction Score: 12.88

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17016423 17139284 11752352

Sources:
TdgClinicalTrial TEND
ANISINDIONE GC

Interaction Score: 1.47

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Vitamin K-dependent gamma-carboxylase inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
ANISINDIONE F2

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
ANISINDIONE SMN2

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ANISINDIONE SMN1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ANISINDIONE TP53

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

TEND: ANISINDIONE
- Version: 01-August-2011
Alternate Names:

ANISINDIONE Primary Drug Name

Drug Info:

Year of Approval 1957

Drug Class anticoagulants

Publications:
TdgClinicalTrial: ANISINDIONE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Anticoagulants

Drug Class small molecule

FDA Approval 1957

Publications:
TTD: Anisindione
- Version: 2020.06.01
Alternate Names:

D09WKB TTD Drug ID

Drug Info:

Publications:
DTC: ANISINDIONE
- Version: 02-September-2020
Alternate Names:

CHEMBL712 ChEMBL Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL712
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL712
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:

Mechanism of Interaction	Vitamin K-dependent gamma-carboxylase inhibitor
Direct Interaction	yes

Trial Name	-
Novel drug target	Established target

ANISINDIONE Drug Record

ANISINDIONE chembl:CHEMBL712 Approved

Alternate Names:

Drug Info:

Publications:

ANISINDIONE GGCX

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 17016423 17139284 11752352

Sources: TdgClinicalTrial TEND

ANISINDIONE GC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Mechanism of Interaction Vitamin K-dependent gamma-carboxylase inhibitor Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

ANISINDIONE F2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

ANISINDIONE SMN2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

ANISINDIONE SMN1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

ANISINDIONE TP53

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

TEND: ANISINDIONE

Alternate Names: ANISINDIONE Primary Drug Name

Drug Info: Year of Approval 1957 Drug Class anticoagulants

Publications:

TdgClinicalTrial: ANISINDIONE

Alternate Names:

Drug Info: Drug Indications Anticoagulants Drug Class small molecule FDA Approval 1957

Publications:

TTD: Anisindione

Alternate Names: D09WKB TTD Drug ID

Drug Info:

Publications:

DTC: ANISINDIONE

Alternate Names: CHEMBL712 ChEMBL Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL712

Alternate Names:

Drug Info:

Publications:

ChemblInteractions: CHEMBL712

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17016423 17139284 11752352

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Vitamin K-dependent gamma-carboxylase inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

ANISINDIONE Primary Drug Name

Drug Info:

Year of Approval 1957

Drug Class anticoagulants

Drug Info:

Drug Indications Anticoagulants

Drug Class small molecule

FDA Approval 1957

Alternate Names:

D09WKB TTD Drug ID

Alternate Names:

CHEMBL712 ChEMBL Drug ID