DGIdb - DRONEDARONE Drug Record

DRONEDARONE chembl:CHEMBL184412 Approved

Alternate Names:

DRONEDARONE
SR33589
SR-33589
SR 33589B
N-(2-BUTYL-3-(4-(3-(DIBUTYLAMINO)PROPOXY)BENZOYL)-5-BENZOFURANYL)-METHANESULFONAMIDE
N-(2-BUTYL-3-(P-(3-(DIBUTYLAMINO)PROPOXY)BENZOYL)-5-BENZOFURANYL)METHANESULFONAMIDE
MULTAQ®
SR-33598B
SR 33589
rxcui:233698
chemidplus:141626-36-0
pubchem.compound:208898
chembl:CHEMBL184412
drugbank:04855

Drug Info:

Drug Class	anti-arrhythmia agents
Year of Approval	2009
FDA Approval	2009
Drug Class	small molecule
Drug Indications	Anti-Arrhythmia Agents

(2 More Sources)

Publications:

Dale et al., 2007, Dronedarone: an amiodarone analog for the treatment of atrial fibrillation and atrial flutter., Ann Pharmacother
Heijman J et al., 2013, Pleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillation., Clin Med Insights Cardiol
Iwamoto et al., 2007, Na+/Ca2+ exchange inhibitors: a new class of calcium regulators., Cardiovasc Hematol Disord Drug Targets

DRONEDARONE KCNA5

Interaction Score: 0.7

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
TTD
DRONEDARONE ADRB1

Interaction Score: 0.37

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17389667 23997577

Sources:
TdgClinicalTrial TEND
DRONEDARONE CALCA

Interaction Score: 0.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
DRONEDARONE ADRA1A

Interaction Score: 0.36

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17389667 23997577

Sources:
TdgClinicalTrial TEND
DRONEDARONE KCNH2

Interaction Score: 0.09

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17896959 23997577

Sources:
TdgClinicalTrial TEND
DRONEDARONE CYP2D6

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
DRONEDARONE AR

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DRONEDARONE CYP3A4

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB

TEND: DRONEDARONE
- Version: 01-August-2011
Alternate Names:

DRONEDARONE Primary Drug Name

Drug Info:

Year of Approval 2009

Drug Class anti-arrhythmia agents

Publications:
TdgClinicalTrial: DRONEDARONE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Anti-Arrhythmia Agents

Drug Class small molecule

FDA Approval 2009

Publications:
DTC: DRONEDARONE
- Version: 02-September-2020
Alternate Names:

CHEMBL184412 ChEMBL Drug ID

Drug Info:

Publications:
TTD: Dronedarone
- Version: 2020.06.01
Alternate Names:

D05CPV TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL184412
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
PharmGKB: dronedarone
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target

Trial Name	-
Novel drug target	Established target

Trial Name	-
Novel drug target	Established target

DRONEDARONE Drug Record

DRONEDARONE chembl:CHEMBL184412 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 17389667 23997577

Sources: TdgClinicalTrial TEND

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 17389667 23997577

Sources: TdgClinicalTrial TEND

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 17896959 23997577

Sources: TdgClinicalTrial TEND

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

TEND: DRONEDARONE

Alternate Names: DRONEDARONE Primary Drug Name

Drug Info: Year of Approval 2009 Drug Class anti-arrhythmia agents

Publications:

TdgClinicalTrial: DRONEDARONE

Alternate Names:

Drug Info: Drug Indications Anti-Arrhythmia Agents Drug Class small molecule FDA Approval 2009

Publications:

DTC: DRONEDARONE

Alternate Names: CHEMBL184412 ChEMBL Drug ID

Drug Info:

Publications:

TTD: Dronedarone

Alternate Names: D05CPV TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL184412

Alternate Names:

Drug Info:

Publications:

PharmGKB: dronedarone

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17389667 23997577

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17389667 23997577

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
17896959 23997577

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Alternate Names:

DRONEDARONE Primary Drug Name

Drug Info:

Year of Approval 2009

Drug Class anti-arrhythmia agents

Drug Info:

Drug Indications Anti-Arrhythmia Agents

Drug Class small molecule

FDA Approval 2009

Alternate Names:

CHEMBL184412 ChEMBL Drug ID

Alternate Names:

D05CPV TTD Drug ID