DGIdb - FENOLDOPAM Drug Record

FENOLDOPAM chembl:CHEMBL588 Approved

Alternate Names:

SK-82526
SK&F-82526
FENOLDOPAM
CORLOPAM®
SK-82526-J
SK&F-82526J
FENOLDOPAMUM
FÉNOLDOPAM
chembl:CHEMBL588
rxcui:24853
chemidplus:67227-56-9
pubchem.compound:3341
drugbank:00800

Drug Info:

FDA Approval	approved
Drug Class	Small Molecule
Drug Indications	antihypertensive agent
Drug Class	antihypertensive agents
Year of Approval	1997

(1 More Sources)

Publications:

Dhasmana et al., The role of dopamine (D2), alpha and beta-adrenoceptor receptors in the decrease in gastrointestinal transit induced by dopamine and dopamine-related drugs in the rat., Pharmacol. Res.
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Zeng et al., 2009, D1-like receptors inhibit insulin-induced vascular smooth muscle cell proliferation via down-regulation of insulin receptor expression., J. Hypertens.
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Martin et al., 1995, Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade., Br. J. Pharmacol.

FENOLDOPAM DRD5

Interaction Score: 3.57

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name fenoldopam mesylate, SKF-82526,Corlopam

PMIDs:
8103596 17016423 17139284 19293728

Sources:
TdgClinicalTrial TEND
FENOLDOPAM ADRA2B

Interaction Score: 0.63

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

PMIDs:
17016423 17139284 7670737

Sources:
TEND
FENOLDOPAM ADRA2C

Interaction Score: 0.5

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

PMIDs:
17016423 17139284 7670737

Sources:
TEND
FENOLDOPAM ADRA2A

Interaction Score: 0.44

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

PMIDs:
17016423 17139284 7670737

Sources:
TEND
FENOLDOPAM DRD1

Interaction Score: 0.35

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name fenoldopam mesylate, SKF-82526,Corlopam

PMIDs:
8103596 11752352 19293728

Sources:
DTC TdgClinicalTrial TEND TTD
FENOLDOPAM RECQL

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FENOLDOPAM CBX1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FENOLDOPAM EHMT2

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

TEND: FENOLDOPAM
- Version: 01-August-2011
Alternate Names:

FENOLDOPAM Primary Drug Name

Drug Info:

Year of Approval 1997

Drug Class antihypertensive agents

Publications:
TdgClinicalTrial: FENOLDOPAM
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications antihypertensive agent

Drug Class Small Molecule

FDA Approval approved

Publications:
TTD: Fenoldopam
- Version: 2020.06.01
Alternate Names:

D0R6BI TTD Drug ID

Drug Info:

Publications:
DTC: FENOLDOPAM
- Version: 02-September-2020
Alternate Names:

CHEMBL588 ChEMBL Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL588
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Novel drug target	Established target
Trial Name	fenoldopam mesylate, SKF-82526,Corlopam

FENOLDOPAM Drug Record

FENOLDOPAM chembl:CHEMBL588 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: agonist (activating)

Interaction Info: Novel drug target Established target Trial Name fenoldopam mesylate, SKF-82526,Corlopam

PMIDs: 8103596 17016423 17139284 19293728

Sources: TdgClinicalTrial TEND

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info:

PMIDs: 17016423 17139284 7670737

Sources: TEND

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info:

PMIDs: 17016423 17139284 7670737

Sources: TEND

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info:

PMIDs: 17016423 17139284 7670737

Sources: TEND

Interaction Types & Directionality: agonist (activating)

Interaction Info: Novel drug target Established target Trial Name fenoldopam mesylate, SKF-82526,Corlopam

PMIDs: 8103596 11752352 19293728

Sources: DTC TdgClinicalTrial TEND TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

TEND: FENOLDOPAM

Alternate Names: FENOLDOPAM Primary Drug Name

Drug Info: Year of Approval 1997 Drug Class antihypertensive agents

Publications:

TdgClinicalTrial: FENOLDOPAM

Alternate Names:

Drug Info: Drug Indications antihypertensive agent Drug Class Small Molecule FDA Approval approved

Publications:

TTD: Fenoldopam

Alternate Names: D0R6BI TTD Drug ID

Drug Info:

Publications:

DTC: FENOLDOPAM

Alternate Names: CHEMBL588 ChEMBL Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL588

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name fenoldopam mesylate, SKF-82526,Corlopam

PMIDs:
8103596 17016423 17139284 19293728

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

antagonist (inhibitory)

PMIDs:
17016423 17139284 7670737

Sources:
TEND

Interaction Types & Directionality:

antagonist (inhibitory)

PMIDs:
17016423 17139284 7670737

Sources:
TEND

Interaction Types & Directionality:

antagonist (inhibitory)

PMIDs:
17016423 17139284 7670737

Sources:
TEND

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name fenoldopam mesylate, SKF-82526,Corlopam

PMIDs:
8103596 11752352 19293728

Sources:
DTC TdgClinicalTrial TEND TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

FENOLDOPAM Primary Drug Name

Drug Info:

Year of Approval 1997

Drug Class antihypertensive agents

Drug Info:

Drug Indications antihypertensive agent

Drug Class Small Molecule

FDA Approval approved

Alternate Names:

D0R6BI TTD Drug ID

Alternate Names:

CHEMBL588 ChEMBL Drug ID