DRD5 Gene Record

  • CARPHENAZINE   DRD5

    Interaction Score: 5.95

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    4889058 4861216 4887393


    Sources:
    TdgClinicalTrial TEND

  • ZUCLOPENTHIXOL   DRD5

    Interaction Score: 3.8

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    10222441 1822319


    Sources:
    TdgClinicalTrial TEND

  • FENOLDOPAM   DRD5

    Interaction Score: 3.57

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Novel drug target Established target
    Trial Name fenoldopam mesylate, SKF-82526,Corlopam

    PMIDs:
    8103596 17016423 17139284 19293728


    Sources:
    TdgClinicalTrial TEND

  • APOMORPHINE   DRD5

    Interaction Score: 1.36

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:

    PMIDs:
    18691132 11752352 15037665


    Sources:
    TEND

  • PHENYLTOLOXAMINE   DRD5

    Interaction Score: 1.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • ETILEVODOPA   DRD5

    Interaction Score: 0.95

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Established target
    Trial Name etilevodopa, TV-1203

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • PERGOLIDE MESYLATE   DRD5

    Interaction Score: 0.68

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Dopamine receptor agonist

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • MELEVODOPA   DRD5

    Interaction Score: 0.68

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name V-1512, CHF-1512,Levomet Complex, Sirio
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • LEVODOPA   DRD5

    Interaction Score: 0.53

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Trial Name entacapone/levodopa/carbidopa,Stalevo
    Novel drug target Established target
    Trial Name levodopa + carbidopa,Duodopa

    PMIDs:
    9633680 18549347 11978145


    Sources:
    TdgClinicalTrial

  • ERGOLOID MESYLATES   DRD5

    Interaction Score: 0.4

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Dopamine receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • AMOXAPINE   DRD5

    Interaction Score: 0.34

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Dopamine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • OLANZAPINE   DRD5

    Interaction Score: 0.28

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name olanzapine,Zyprexa, Zypadhera, Zyprexa Relprevv
    Novel drug target Established target
    Trial Name Olanzapine/fluoxetine combination,Symbyax (Zyprexa/Prozac)

    PMIDs:
    17848919 10227113 25032030


    Sources:
    TdgClinicalTrial

  • PIMOZIDE   DRD5

    Interaction Score: 0.18

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Dopamine receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000169676

    • Version: 101_38

    Alternate Names:
    DRD5 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TEND: P21918

    • Version: 01-August-2011

    Alternate Names:
    1816 Entrez Gene Id
    DRD5_HUMAN Uniprot Id
    DRD5 Gene Symbol

    Gene Info:
    Transmembrane Helix Count 6
    Target Subclass GPCR
    Target Subclass Rhodopsin

    Publications:

  • TdgClinicalTrial: P21918

    • Version: January-2014

    Alternate Names:
    DRD5 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin

    Publications:

  • RussLampel: ENSG00000169676

    • Version: 26-July-2011

    Alternate Names:
    DRD5 Display Id
    D(1B) DOPAMINE RECEPTOR (D(5) DOPAMINE RECEPTOR) (D1BETA DOPAMINE RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P21918] Description
    ENSG00000169676 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: P21918

    • Version: 11-September-2012

    Alternate Names:
    DRD5_HUMAN Uniprot Id
    ENSG00000169676 Ensembl Gene Id
    1816 Entrez Gene Id

    Gene Info:
    Interpro Acc IPR000276
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name 7TM_GPCR_Rhodpsn

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

  • CIViC: DRD5

    • Version: 14-September-2020

    Alternate Names:
    1816 Entrez Gene ID
    1536 CIViC Gene ID

    Gene Info:

    Publications:
    Prabhu VV et al., 2019, Dopamine Receptor D5 is a Modulator of Tumor Response to Dopamine Receptor D2 Antagonism., Clin Cancer Res

  • HingoraniCasas: ENSG00000169676

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000169676 Gene Symbol
    DRD5 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: DRD1B

    • Version: chembl_23

    Alternate Names:
    DRD1L2 GENE_SYMBOL
    DRD5 GENE_SYMBOL
    D(1B) dopamine receptor UNIPROT

    Gene Info:

    Publications:

  • GO: DRD5

    • Version: 01-February-2022

    Alternate Names:
    DRD1B GO Gene Synonym
    DRD1L2 GO Gene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

  • dGene: DRD5

    • Version: 27-Jun-2013

    Alternate Names:
    1816 Gene ID
    DBDR dGene Synonym
    DRD1B dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

  • TTD: Dopamine D5 receptor

    • Version: 2020.06.01

    Alternate Names:
    D5R TTD Gene Abbreviation
    T46828 TTD Target ID

    Gene Info:

    Publications: