AVAGACESTAT Drug Record

  • AVAGACESTAT chembl:CHEMBL1090771

    Alternate Names:

    BMS-708163-01
    BMS-708163
    BMS 708163
    AVAGACESTAT
    BMS-70816301

    Drug Info:

    FDA Approval not approved
    Drug Class Small molecule
    Drug Indications for treatment of alzheimer's disease
    (0 More Sources)

    Publications:

  • AVAGACESTAT   NCSTN

    Interaction Score: 2.21

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Gamma-secretase inhibitor
    Direct Interaction yes
    Trial Name BMS-708163

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • AVAGACESTAT   AD5

    Interaction Score: 2.21

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Gamma-secretase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • AVAGACESTAT   PSEN1

    Interaction Score: 2.21

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name BMS-708163
    Novel drug target Novel Target
    Mechanism of Interaction Gamma-secretase inhibitor

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • AVAGACESTAT   APH1B

    Interaction Score: 1.96

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Gamma-secretase inhibitor
    Trial Name BMS-708163

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • AVAGACESTAT   PSENEN

    Interaction Score: 1.96

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Gamma-secretase inhibitor
    Trial Name BMS-708163

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • AVAGACESTAT   APH1A

    Interaction Score: 1.77

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Gamma-secretase inhibitor
    Trial Name BMS-708163

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • AVAGACESTAT   PSEN2

    Interaction Score: 1.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name BMS-708163
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial