• Interaction Score: 7.07

    Interaction Types & Directionality:
    activator (activating)
    positive modulator (activating)
    agonist (activating)
    stimulator (activating)

    Interaction Info:
    Novel drug target Established target
    Trial Name riociguat, BAY-63-2521
    Mechanism of Interaction Soluble guanylate cyclase positive allosteric modulator

  • Interaction Score: 6.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 4.12

    Interaction Types & Directionality:
    activator (activating)
    positive modulator (activating)

    Interaction Info:
    Trial Name riociguat, BAY-63-2521
    Novel drug target Novel Target
    Mechanism of Interaction Soluble guanylate cyclase positive allosteric modulator

    PMIDs:
    None found


  • Interaction Score: 4.12

    Interaction Types & Directionality:
    positive modulator (activating)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name riociguat, BAY-63-2521
    Mechanism of Interaction Soluble guanylate cyclase positive allosteric modulator

    PMIDs:
    None found


  • Interaction Score: 3.53

    Interaction Types & Directionality:
    activator (activating)
    positive modulator (activating)

    Interaction Info:
    Mechanism of Interaction Soluble guanylate cyclase positive allosteric modulator
    Direct Interaction yes
    Novel drug target Novel Target

    PMIDs:
    None found