DESFLURANE |
SUPRANE |
I-653 |
DESFLURANO |
DIFLUOROMETHYL 1,2,2,2-TETRAFLUOROETHYL ETHER |
DESFLURANUM |
1,1,1,2-TETRAFLUORO-2-(DIFLUOROMETHOXY)ETHANE |
HFE-236EA2 |
(+-)-2-DIFLUOROMETHYL 1,2,2,2-TETRAFLUOROETHYL ETHER |
SUPRANE® |
rxcui:27340 |
pubchem.compound:42113 |
drugbank:01189 |
chembl:CHEMBL1200733 |
chemidplus:57041-67-5 |
Drug Class | anesthetics, inhalation |
Year of Approval | 1992 |
FDA Approval | 1992 |
Drug Class | small molecule |
Drug Indications | inhalation anesthetics |
n/a |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
other/unknown |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Glycine receptor (alpha-1/beta) positive modulator |
inducer (activating) |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
n/a |
Mechanism of Interaction | Potassium channel subfamily K member 18 opener |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Potassium channel subfamily K member 10 opener |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Potassium channel subfamily K member 9 opener |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Potassium channel subfamily K member 2 opener |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Potassium channel subfamily K member 3 opener |
Direct Interaction | yes |
n/a |
Direct Interaction | yes |
Mechanism of Interaction | Glycine receptor (alpha-1/beta) positive modulator |
positive modulator (activating) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
DESFLURANE | Primary Drug Name |
Year of Approval | 1992 |
Drug Class | anesthetics, inhalation |
Drug Indications | inhalation anesthetics |
Drug Class | small molecule |
FDA Approval | 1992 |
D0H4GN | TTD Drug ID |