COMPOUND 469 |
ISOFLURANE |
AERRANE |
COMPOUND-469 |
FORANE |
FORENE |
1-CHLORO-2,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER |
ISOFLURANO |
ISOFLURANUM |
HCFE-235DA2 |
drugbank:00753 |
chembl:CHEMBL1256 |
rxcui:6026 |
pubchem.compound:3763 |
chemidplus:26675-46-7 |
FDA Approval | 1979 |
Drug Class | small molecule |
Drug Indications | Anesthetics, Inhalation |
Year of Approval | 1979 |
Drug Class | anesthetics, inhalation |
n/a |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Novel drug target | Established target |
Trial Name | - |
Direct Interaction | yes |
inducer (activating) |
Novel drug target | Established target |
Trial Name | - |
n/a |
Mechanism of Interaction | Potassium channel subfamily K member 18 opener |
Direct Interaction | yes |
n/a |
Direct Interaction | yes |
Mechanism of Interaction | Potassium channel subfamily K member 10 opener |
n/a |
Mechanism of Interaction | Potassium channel subfamily K member 9 opener |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
activator (activating) |
Mechanism of Interaction | Potassium channel subfamily K member 2 opener |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Potassium channel subfamily K member 3 opener |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Glycine receptor (alpha-1/beta) positive modulator |
Direct Interaction | yes |
positive modulator (activating) |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
positive modulator (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive allosteric modulator |
Direct Interaction | yes |
ISOFLURANE | Primary Drug Name |
Drug Class | anesthetics, inhalation |
Year of Approval | 1979 |
Drug Indications | Anesthetics, Inhalation |
Drug Class | small molecule |
FDA Approval | 1979 |
D0DP6L | TTD Drug ID |