DGIdb - MASITINIB Drug Record

MASITINIB chembl:CHEMBL1908391 Antineoplastic

Alternate Names:

MASITINIB
KINAVET
AB-1010
MASIVET
AB 1010
AB1010
MASICAN® (PROPOSED TRADE NAME)
drugbank:11526
chembl:CHEMBL1908391
pubchem.compound:10074640
chemidplus:790299-79-5

Drug Info:

Drug Class	Kinase Inhibitors
FDA Approval	not approved
Drug Class	Small molecule
Drug Indications	antiinflammatory agent,DMARD,antineoplastic agent
Pharmaceutical Developer	AB Science
Source Reported Drug Name(s)	Masitinib
Drug Class	Kit Inhibitor

(4 More Sources)

Publications:

MASITINIB KIT

Interaction Score: 0.36

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name masitinib, AB1010

Reported Cancer Type Melanoma

PMIDs:
None found

Sources:
MyCancerGenome TdgClinicalTrial ChemblInteractions CancerCommons MyCancerGenomeClinicalTrial
MASITINIB PTK2B

Interaction Score: 0.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
MASITINIB HCK

Interaction Score: 0.25

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial
MASITINIB LYN

Interaction Score: 0.22

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial MyCancerGenomeClinicalTrial
MASITINIB FGFR3

Interaction Score: 0.21

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Fibroblast growth factor receptor 3 inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial
MASITINIB PDGFRA

Interaction Score: 0.21

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name masitinib, AB1010

Mechanism of Interaction Platelet-derived growth factor receptor inhibitor

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions MyCancerGenomeClinicalTrial
MASITINIB PDGFRB

Interaction Score: 0.19

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Established target

Direct Interaction yes

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions MyCancerGenomeClinicalTrial
MASITINIB PTK2

Interaction Score: 0.17

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
MASITINIB SRC

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TTD
MASITINIB CSF1R

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial
MASITINIB FGFR2

Interaction Score: 0.09

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
MASITINIB ABL1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial
MASITINIB FGFR1

Interaction Score: 0.05

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
MyCancerGenome
MASITINIB YES1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

CancerCommons: MASITINIB
- Version: 25-July-2013
Alternate Names:

Masitinib PubChem Drug Name

10074640 PubChem Drug ID

Masitinib Drug Trade Name

Drug Info:

Drug Class Kit Inhibitor

Source Reported Drug Name(s) Masitinib

Pharmaceutical Developer AB Science

Publications:
MyCancerGenome: MASITINIB
- Version: 20-Jun-2017
Alternate Names:

AB1010 Development Name

MASITINIB Generic Name

MASIVET Trade Name

Drug Info:

Drug Class Kinase Inhibitors

Publications:
TdgClinicalTrial: MASITINIB
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications antiinflammatory agent,DMARD,antineoplastic agent

Drug Class Small molecule

FDA Approval not approved

Publications:
TTD: Masitinib
- Version: 2020.06.01
Alternate Names:

D0MW0N TTD Drug ID

Drug Info:

Publications:
DTC: MASITINIB
- Version: 02-September-2020
Alternate Names:

CHEMBL1908391 ChEMBL Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1908391
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL1908391
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:
MyCancerGenomeClinicalTrial: MASITINIB
- Version: 30-February-2014
Alternate Names:

Drug Info:

Publications:

Novel drug target	Established target
Trial Name	masitinib, AB1010
Reported Cancer Type	Melanoma

Direct Interaction	yes
Mechanism of Interaction	Fibroblast growth factor receptor 3 inhibitor

Masitinib	PubChem Drug Name
10074640	PubChem Drug ID
Masitinib	Drug Trade Name

AB1010	Development Name
MASITINIB	Generic Name
MASIVET	Trade Name

MASITINIB Drug Record

MASITINIB chembl:CHEMBL1908391 Antineoplastic

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Novel drug target Established target Trial Name masitinib, AB1010 Reported Cancer Type Melanoma

PMIDs: None found

Sources: MyCancerGenome TdgClinicalTrial ChemblInteractions CancerCommons MyCancerGenomeClinicalTrial

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info: Trial Name masitinib, AB1010 Novel drug target Novel Target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Trial Name masitinib, AB1010 Novel drug target Novel Target

PMIDs: None found

Sources: TdgClinicalTrial MyCancerGenomeClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Fibroblast growth factor receptor 3 inhibitor

PMIDs: None found

Sources: MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Novel drug target Established target Trial Name masitinib, AB1010 Mechanism of Interaction Platelet-derived growth factor receptor inhibitor

PMIDs: None found

Sources: TdgClinicalTrial ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Trial Name masitinib, AB1010 Novel drug target Established target Direct Interaction yes

PMIDs: None found

Sources: TdgClinicalTrial ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: MyCancerGenome

Interaction Types & Directionality: n/a

Interaction Info: Trial Name masitinib, AB1010 Novel drug target Established target

PMIDs: None found

Sources: TdgClinicalTrial TTD

Interaction Types & Directionality: n/a

Interaction Info: Trial Name masitinib, AB1010 Novel drug target Established target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: MyCancerGenome

Interaction Types & Directionality: n/a

Interaction Info: Trial Name masitinib, AB1010 Novel drug target Established target

PMIDs: None found

Sources: TdgClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: None found

Sources: MyCancerGenome

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

CancerCommons: MASITINIB

Alternate Names: Masitinib PubChem Drug Name 10074640 PubChem Drug ID Masitinib Drug Trade Name

Drug Info: Drug Class Kit Inhibitor Source Reported Drug Name(s) Masitinib Pharmaceutical Developer AB Science

Publications:

MyCancerGenome: MASITINIB

Alternate Names: AB1010 Development Name MASITINIB Generic Name MASIVET Trade Name

Drug Info: Drug Class Kinase Inhibitors

Publications:

TdgClinicalTrial: MASITINIB

Alternate Names:

Drug Info: Drug Indications antiinflammatory agent,DMARD,antineoplastic agent Drug Class Small molecule FDA Approval not approved

Publications:

TTD: Masitinib

Alternate Names: D0MW0N TTD Drug ID

Drug Info:

Publications:

DTC: MASITINIB

Alternate Names: CHEMBL1908391 ChEMBL Drug ID

Drug Info:

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name masitinib, AB1010

Reported Cancer Type Melanoma

PMIDs:
None found

Sources:
MyCancerGenome TdgClinicalTrial ChemblInteractions CancerCommons MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Fibroblast growth factor receptor 3 inhibitor

PMIDs:
None found

Sources:
MyCancerGenome ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name masitinib, AB1010

Mechanism of Interaction Platelet-derived growth factor receptor inhibitor

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Established target

Direct Interaction yes

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions MyCancerGenomeClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
MyCancerGenome

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TTD

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
MyCancerGenome

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name masitinib, AB1010

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
MyCancerGenome

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

Masitinib PubChem Drug Name

10074640 PubChem Drug ID

Masitinib Drug Trade Name

Drug Info:

Drug Class Kit Inhibitor

Source Reported Drug Name(s) Masitinib

Pharmaceutical Developer AB Science

Alternate Names:

AB1010 Development Name

MASITINIB Generic Name

MASIVET Trade Name

Drug Info:

Drug Class Kinase Inhibitors

Drug Info:

Drug Indications antiinflammatory agent,DMARD,antineoplastic agent

Drug Class Small molecule

FDA Approval not approved

Alternate Names:

D0MW0N TTD Drug ID

Alternate Names:

CHEMBL1908391 ChEMBL Drug ID