DEPSIPEPTIDE |
ISTODAX |
ROMIDEPSIN |
FR-901228 |
FK-228 |
NSC-630176 |
CHROMADAX |
ANTIBIOTIC FR 901228 |
ISTODAX® |
FR901228 |
FK228 |
chemidplus:128517-07-7 |
chembl:CHEMBL343448 |
pubchem.compound:5352062 |
rxcui:877510 |
Drug Class | antineoplastic agents |
Year of Approval | 2009 |
FDA Approval | Cutaneous T-cell lymphoma, Peripheral T-cell lymphoma |
Drug Class | Small molecule inhibitor |
FDA Approval | approved |
Drug Class | small molecule |
Drug Indications | antineoplastic agent |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | Depsipeptide |
Mechanism of Interaction | Histone deacetylase inhibitor |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Trial Name | Depsipeptide |
Novel drug target | Established target |
Notes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
Trial Name | Depsipeptide |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
Trial Name | Depsipeptide |
inhibitor (inhibitory) |
Trial Name | Depsipeptide |
Novel drug target | Established target |
Mechanism of Interaction | Histone deacetylase inhibitor |
inhibitor (inhibitory) |
Trial Name | Depsipeptide |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
Trial Name | Depsipeptide |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | Depsipeptide |
Mechanism of Interaction | Histone deacetylase inhibitor |
n/a |
Evidence Type | Actionable |
Approval Status | Preclinical |
Response Type | sensitive |
ISTODAX | Trade Name |
Drug Class | Small molecule inhibitor |
FDA Approval | Cutaneous T-cell lymphoma, Peripheral T-cell lymphoma |
ROMIDEPSIN | Primary Drug Name |
Year of Approval | 2009 |
Drug Class | antineoplastic agents |
Drug Indications | antineoplastic agent |
Drug Class | small molecule |
FDA Approval | approved |
C1544 | NCI drug code |
C1544 | NCI drug code |
CHEMBL1213490 | ChEMBL Drug ID |
ROMIDEPSIN | Primary Drug Name |
ROMIDEPSIN | Drug Generic Name |
ISTODAX | Drug Trade Name |
D0L7LC | TTD Drug ID |