RWJ-17021-000 |
MCN-4853 |
QUDEXY XR |
TROKENDI XR |
USL255 |
RWJ-17021 |
EPITOMAX |
TOPAMAX |
USL-255 |
TOPAMAX SPRINKLE |
TOPIRAMATE |
2,3:4,5-DI-O-ISOPROPYLIDENE-BETA-D-FRUCTOPYRANOSE SULFAMATE |
TPM |
TOPAMAX® |
TIPIRAMATE |
[(1R,2S,6S,9R)-4,4,11,11-TETRAMETHYL-3,5,7,10,12-PENTAOXATRICYCLO[7.3.0.0^{2,6}]DODECAN-6-YL]METHYL SULFAMATE |
TIPIRAMATO |
2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-BETA-D-FRUCTOPYRANOSE SULFAMATE |
TOPOMAX |
TOPIRAMATUM |
TOPIRAMATO |
chemidplus:97240-79-4 |
drugbank:00273 |
pubchem.compound:5284627 |
rxcui:38404 |
chembl:CHEMBL220492 |
Drug Class | anticonvulsants |
Drug Class | anti-migraine agents |
Year of Approval | 1996 |
FDA Approval | 1996 |
Drug Indications | anti-migraine agents |
Drug Indications | Anticonvulsants |
Drug Indications | anticonvulsant,antimigraine agent |
FDA Approval | approved |
Drug Class | small molecule |
Drug Indications | anticonvulsant |
antagonist (inhibitory) |
Trial Name | topiramate controlled release,Trokesa |
Novel drug target | Established target |
Trial Name | topiramate tablet,Topamax |
inhibitor (inhibitory) |
Mechanism of Interaction | Carbonic anhydrase IV inhibitor |
Direct Interaction | yes |
Trial Name | topiramate controlled release,Trokesa |
inhibitor (inhibitory) |
Trial Name | topiramate controlled release,Trokesa |
Novel drug target | Established target |
Trial Name | topiramate tablet,Topamax |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate receptor ionotropic kainate antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glutamate receptor ionotropic kainate antagonist |
blocker (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
Trial Name | topiramate controlled release,Trokesa |
positive modulator (activating) |
agonist (activating) |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
Trial Name | topiramate controlled release,Trokesa |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate receptor ionotropic AMPA antagonist |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Glutamate receptor ionotropic kainate antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate receptor ionotropic AMPA antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate receptor ionotropic AMPA antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Glutamate receptor ionotropic AMPA antagonist |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
n/a |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
n/a |
Direct Interaction | yes |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | GABA-A receptor; anion channel positive modulator |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
TOPIRAMATE | Primary Drug Name |
Year of Approval | 1996 |
Drug Class | anti-migraine agents |
Drug Class | anticonvulsants |
Drug Indications | anticonvulsant |
Drug Class | small molecule |
FDA Approval | approved |
CHEMBL220492 | ChEMBL Drug ID |
D07VDZ | TTD Drug ID |