TEZAMPANEL Drug Record

  • TEZAMPANEL chembl:CHEMBL14935

    Alternate Names:

    NGX-424
    LY-293558
    LY-293,558

    Drug Info:

    FDA Approval not approved
    Drug Class small molecule
    Drug Indications antimigraine agent,analgesic
    (0 More Sources)

    Publications:

  • TEZAMPANEL   GRIK5

    Interaction Score: 6.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name tezampanel, NGX424,NGX426
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • TEZAMPANEL   GRIK3

    Interaction Score: 4.58

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name tezampanel, NGX424,NGX426
    Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • TEZAMPANEL   GRIK1

    Interaction Score: 4.12

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist
    Trial Name tezampanel, NGX424,NGX426

    PMIDs:
    10592235


    Sources:
    TdgClinicalTrial ChemblInteractions

  • TEZAMPANEL   GRIK4

    Interaction Score: 3.43

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist
    Direct Interaction yes
    Trial Name tezampanel, NGX424,NGX426

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • TEZAMPANEL   GRIA4

    Interaction Score: 0.98

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Glutamate receptor ionotropic AMPA antagonist
    Direct Interaction yes
    Trial Name tezampanel, NGX424,NGX426

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • TEZAMPANEL   GRIK2

    Interaction Score: 0.92

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist
    Direct Interaction yes
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • TEZAMPANEL   GRIA3

    Interaction Score: 0.81

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name tezampanel, NGX424,NGX426
    Novel drug target Established target
    Mechanism of Interaction Glutamate receptor ionotropic AMPA antagonist

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • TEZAMPANEL   GRIA1

    Interaction Score: 0.57

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name tezampanel, NGX424,NGX426
    Novel drug target Established target
    Mechanism of Interaction Glutamate receptor ionotropic AMPA antagonist

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • TEZAMPANEL   GRIA2

    Interaction Score: 0.49

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name tezampanel, NGX424,NGX426
    Novel drug target Established target
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions